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Pentoxifylline
| Question | Answer |
|---|---|
| Pentoxifylline T, P | T: Intermittent Claudication P: Coagulation modifier/platelet aggregate inhibitor |
| Pentoxifylline MOA | Reduces viscosity of RBC and increases flexibility. Allows RBCs to enter partially occluded vessels. Reduces hypoxia and pain in the muscle. |
| SE of Pentoxifylline | Dyspepsia, N/V, dizziness, myalgia, HA, CNS, effects, heart failure, MI |
| Contraindications to Pentoxifylline | Do not use if allergic to caffeine or theophylline. DO not use for recent bleeding in brain or retina. |
| Nursing considerations | Monitor for bleeding, if taking blood thinner, may need frequent PT/INR monitoring. |