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Entresto
| Question | Answer |
|---|---|
| Entresto Therapeutic use | Chronic heart failure |
| Entresto pharmacologic | neprilysin inhibitor (sacubitril) and ARB(Valsartan) |
| MOA of entresto | Increase the amount of beneficial natriuretic peptides in the blood |
| Uses of entresto | reduces risk of cardiovascular death and hospitalization in pts with chronic HF |
| Side effects of entresto | Hyperkalemia, hypoglycemia, hypotension, renal failure, hepatitis, rhabdomyolysis, thrombocytopenia, neutropenia, cough, dizziness, and lightheadedness. |
| Contraindications to entresto | Hx of angioedema, pregnancy, breastfeeding |
| Nursing considerations for entresto | do not administer within 36 hours of an ace inhibitor BP, renal Liquid form if cant swallow Avoid potassium supplements and salt substitutes Change positions slowly |