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Nuerotransmitters
| Question | Answer |
|---|---|
| Acetylcholine | function: MUSCLE action, learning, memory malfunction ex: Alzheimer's - nuerons deteriorate |
| Dopamine | function: influences movement, LEARNING, attention, emotion malfunction ex:schizophrenia and parkinsons *addiction |
| Serotonin | function: affects mood, hunger, SLEEP, arousal malfunction ex: undersupply linked to depression |
| Norepinephrine | function: alertness and AROUSAL malfunction ex: undersupply can depress mood |
| GABA | function: inhibitory nuerotransmitter malfunction ex: seizures, tremors, insomnia |
| Glutamate | function: EXCITATORY nuerotransmitter, MEMORY malfunction ex: migraines |
| Endorphins | function: perception PAIN or pleasure malfunction ex: oversupply of drugs suppresses body's natural amount |
| Substance P | function: PAIN perception and immune response malfunction ex: chronic pain |
| Nueron | nerve cell that is the basic building block of the nervous system |
| Soma | part of the neuron that contains the nucleus |
| Dendrites | bushy, branching extensions that receive and integrate messages, conducting impulses toward the cell body. |
| Axon | neuron extension that passes messages through its branches to other neurons or to muscles or glands. |
| Myelin Sheath | the fatty tissue layer that segmentally covers the axons of some neurons. It increases transmission speed and provides insulation. |
| Terminal Branches | the ends of the axon containing terminal buttons which hold synaptic vesicles that store neurotransmitters. |
| Glial Cells | cells that support, nourish, and protect neurons. They also play a role in learning, thinking, and memory. |
| threshold | level of stimulation required to trigger a neural impulse. |
| polarization | A resting neuron has negatively charged ions inside the axon and positively charged ions outside the axon. |
| depolarization | When the electrical charge reaches -55 mV, the axon gates open, allowing the ions to mix inside the axon. |
| excitatory signal | Like the gas pedal on a car. Excitatory neurotransmitter signals trigger action. |
| Inhibitory signal | Like the brake pedal on a car. Inhibitory neurotransmitter signals depress action. |
| When the excitatory impulses ________ the inhibitory impulses, the threshold has been reached and an action potential occurs. | outnumber |
| action potential | a neural impulse; a brief electrical charge that travels down the axon. |
| refractory period | is a resting pause during which subsequent action potentials cannot occur until the axon returns to its resting state. |
| nuerotransmitter | a chemical messenger that travels across the synapse and binds to receptor sites on the receiving neuron. |
| synapse | the junction between the axon tip of the sending neuron and the dendrite or cell body of the receiving neuron. |
| reuptake | a neurotransmitter's reabsorption by the sending neuron. |
| agonists | increases nuerotransmitter action - exciting nueron firing |
| antagonists | inhibits/blocks nuerotransmitter s action - inhibiting nueron firing |
| adrenal glands | release epinephrine and norepinephrine (adrenaline and noradrenaline) to energize the body. |
| hypothalamus | directs the pituitary gland to regulate growth and control other endocrine glands. |
| psychoactive drugs | Chemical substances that alter perceptions and moods |
| substance abuse disorder | A disorder characterized by continued substance craving and use despite significant life disruption and/or physical risk |
| tolerance | The diminishing effect with regular use of the same dose of a drug, requiring the user to take larger and larger doses before experiencing the drug’s effect |
| addiction | A primary, chronic disease of brain reward, motivation, memory and related circuitry |
| nueroadaptation | The brain alters its chemistry and structure to try and balance the overwhelming surges of chemicals caused by repeated drug use. |
| withdrawl | The discomfort and distress that follow discontinuing an addictive drug or behavior |
| 3 major categories of psychoactive drugs | depressents, stimulants, hallucinogens |
| depresents | Drugs (such as alcohol, barbiturates, and opiates) that reduce neural activity and slow body functions |
| expectancy effects | Expectations influence behavior. ex-Simply believing we’re consuming alcohol can cause us to act out alcohol’s presumed influence. |
| barbiturates | Drugs that depress central nervous system activity, reducing anxiety but impairing memory and judgment |
| opiates | Opium and its derivatives, such as morphine and heroin; depress neural activity, temporarily lessening pain and anxiety. |
| stimulates | Drugs (such as caffeine, nicotine, and the morepowerful cocaine, amphetamines, methamphetamine, and Ecstasy) that excite neural activity and speed up body functions |
| A powerful and addictive stimulant derived from the coca plant; produces temporarily increased alertness and euphoria | cocaine |
| methamphetamine | A powerfully addictive drug that stimulates the central nervous system, with accelerated body functions and associated energy and mood changes; over time, appears to reduce baseline dopamine levels |
| Ecstasy (MDMA) | A synthetic stimulant and mild hallucinogen |
| hallucinogens | Psychedelic (“mind-manifesting”) drugs, such as LSD, that distort perceptions and evoke sensory images in the absence of sensory input |
| LSD (or acid) | vary from euphoria to detachment to panic. |
| THC | the psychoactive ingredient in weed |