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Class & Indications
classifications and their specific indications
| Classification | Indication | MOA | Types and Side Effects |
|---|---|---|---|
| Diuretics | high blood pressure, heart failure (Loop) | lowers blood pressure via kidneys removing excess salt and water through urine, decreased fluid volume in blood vessels = decreased pressure against vessel wall | Thiazide and Loop: depletes potassium in body (hypokalemia) Potassium Sparing: maintains |
| ACE Inhibitors | high blood pressure | causes vasodilation via blocking the angiotensin hormone from being produced | persistent dry cough |
| Angiotensin II Receptor Blockers (ARBs) | high blood pressure | causes vasodilation via blocking the receptors for the angiotensin hormone | dizziness, fatigue, headache, swelling of face and tongue |
| Beta-Blockers | high blood pressure, angina (chest pain), myocardial infarction (heart attack) | blocks the effect of epinephrine (adrenaline) on the heart, reduces heart's demand for oxygen | dizziness, dry eyes or mouth, fatigue, low blood pressure |
| Calcium Channel Blockers | high blood pressure, arrythmia (irregular heartbeat) | prevents calcium from entering smooth muscle cells of heart and arteries, causes heart to contract less forcefully and arteries to relax & widen | constipation, swelling in the arms and legs, and slow heart rate |
| HMG-CoA Reductase Inhibitors | high cholesterol | blocks HMG-CoA Reductase enzyme from producing cholesterol in the liver | muscle pain, digestive problems, and mental fuzziness |
| Anticoagulants | clot prevention in deep vein thrombosis (DVT) and atrial fibrillation | interfere with chemical clotting factors in the blood plasma to prevent the formation or growth of clots | |
| Antiplatelets | clot prevention in arteries that cause heart attack and stroke | affect "stickiness" of platelets, preventing clumps |