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CV 3

w/ essential knowledge

GenericBrandCategoryIndicationsSide EffectsUS Box WarningOther Notes
dabigatran (PO) Pradaxa Anticoagulant, direct thrombin inhibitor AF (stroke prevention), VTE bleeding, dyspepsia premature discontinuation increases risk of thrombotic events; increased risk of epidural or spinal hematoma in patients undergoing spinal puncture swallow whole; dispense and store in original packaging; discard 4 months after opening
apixaban (PO) Eliquis Anticoagulant, factor Xa inhibitor AF (stroke prevention), VTE bleeding premature discontinuation increases risk of thrombotic events; increased risk of epidural or spinal hematoma in patient undergoing spinal puncture
rivaroxaban (PO) Xarelto Anticoagulant, factor Xa inhibitor AF (stroke prevention), VTE, PAD bleeding premature discontinuation increases risk of thrombotic events; increased risk of epidural or spinal hematoma in patient undergoing spinal puncture
warfarin (PO) Coumadin, Jantoven Anticoagulant, vitamin K antagonist AF (stroke prevention), VTE bleeding, skin necrosis bleeding risk narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; therapeutic monitoring recommended with INR). dose dependent tablet colors; consistent vitamin K intake recommended; many drug interactions
enoxaparin (SQ) Lovenox Anticoagulant, low molecular weight heparin ACS, VTE bleeding, HIT increased risk of epidural or spinal hematoma in patients undergoing spinal puncture do not expel air bubble from syringe prior to injection
heparin (IV, SQ) --- Anticoagulant ACS, VTE bleeding, hyperkalemia (chronic use), HIT
clopidogrel (PO) Plavix Antiplatelet agent ACS, CAD, stroke bleeding diminished effectiveness in poor metabolizers
ticagrelor (PO) Brilinta Antiplatelet agent ACS bleeding, dyspnea significant, sometimes fatal bleeding; do not exceed aspirin >100 mg daily due to reduced ticagrelor effectiveness
aspirin (PO) (OTC) Bayer, Bufferin, Ecotrin Antiplatelet agent ACS, stable angina, pain, stroke dyspepsia, heartburn, bleeding CI in NSAID or salicylate allergy, children and teenagers with viral infection (due to Reye's syndrome), can cause tinnitus in salicylate overdose
nitroglycerin (SL) Nitrostat Vasodilator ACS, stable angina headache, flushing, syncope, dizziness do not use with PDE-5 inhibitors; tachyphylaxis (tolerance/↓effectiveness); can aggravate angina causes by hypertrophic cardiomyopathy
alteplase (intracatheter, IV) Intracatheter: Cathflo Activase IV: Activase Fibrinolytic Intracatheter: catheter clearance IV: STEMI, acute ischemic stroke, PE bleeding CI in patients with severe uncontrolled HTN
Created by: salmouie
 

 



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