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Chapter 5 Terms
Dosage Forms and routes of Administration
| Question | Answer |
|---|---|
| Absorption | The taking in of nutrients and drugs into the body from food and liquids |
| Behind the counter (BTC) | Nonprescription drugs that are kept behind the pharmacy counter; limited amounts may be sold, or the customer may require the permission of a pharmacist to purchase them |
| Bioavaliabilty | The degree to which a drug or other substance becomes available to the target tissue after administration |
| Bioequivalence | The relationship between two drugs that have the same dosage and dosage form and that have similar bioavailability. Generic versions of a medication must show bioequivalence to the original approved brand product as a requirement of drug approval |
| Distribution | The movement of medication throughout the blood, organs, and tissues after administration |
| Elimination | The final evacuation of a drug or other substance from the body by normal body processes such as kidney elimination(urine), Biliary excretion(bile to stool), sweat, respiration, or saliva |
| Enteral | A route of administration by way of intestine, such as orally, rectally, or sublingually |
| First-pass effect | A process in which a portion of the drug dose is metabolized before the drug has a chance to be distributed systematically |
| Half-life | 1) the time required for a chemical to be decreased by half 2) The time needed / half the amount of a substance, such as a drug in a living system 3) The time required for the concentration of a substance in a body fluid (blood plasma) to decrease by hald |
| Instill | To place into; instillation instructions are commonly used for opthalmic or otic drugs |
| Legend drugs | Drugs that require a prescription; these drugs carry the federal legend: "federal law prohibits the dispensing of this medication without a prescription" |
| Metabolism | The process by which the body breaks down or converts medications to active or inactive substances. The primary site of drug metabolism in humans is the liver; however, select drugs metabolize through other process |
| Over the Counter (OTC) | Medications that can be purchased without a prescription |
| Parenternal | A term used to describe a medication that is usually given by injection into a vein, the skin, the muscle, that bypasses the gastrointestinal system |
| Pharmacokinetics | The study of the absorption, metabolism, distribution, and elimination of drugs |
| Prodrug | An inactive substance that is converted to a drug in the body by the action of enzymes or other chemicals |