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blood bank exam 1
| Question | Answer |
|---|---|
| serology | the science dealing with detection of antibodies in body fluids |
| non-specific immunity | body's natural, fast acting defense system |
| interferon | nonspecific inhibitor of a virus; released from infected cells and absorbed by other cells to prevent infection |
| acquired immunity | specialized defense system that develops as one encounters antigens |
| active immunity | when the immune system produces antibodies after being exposed to a vaccine |
| cell mediated immunity | immune response that utilizes activated immune cells |
| humoral mediated immunity | adaptive immune defense that uses antibodies to target pathogens |
| major histocompatibility complex (MHC) | large group of BM precursors, monocytes, and macrophages, dendritic cells, and specialized macrophages |
| father of immunology | louis pasteur |
| epitope | part of an antigen (Ag) that reacts w/ an antibody or T lymph receptor |
| porphyrin ring | hydrocarbon structure containing an iron atom which binds and releases oxygen as needed |
| what cell can bind and kill microorganisms | neutrophils |
| chemical composition of an antibody | glycoprotein |
| opsonins | proteins that coat foreign cells and act as tags for phagocytes |
| when C3 attaches to a cell it causes | the cell to lyse |
| PEG | antibody potentiating reagent that functions by increasing the rate of antibody uptake |
| how does ficin enhance the antigen-antibody complex formation? | removes the negative charges from the RBCS |
| what about the genetic system makes it a useful marker in paternity testing? | polymorphic |
| direct | proves alleged parent cannot be biological |
| indirect | less definitive evidence based off missing expected traits |
| alleles | alternate forms of a gene at a given loci |
| polymerase chain reaction (PCR) | technique that uses a small amount of DNA and amplifies it for identification |
| when a trait is passed from a father to all of his daughters but none of his son, the trait is | X-linked dominant |
| A antigen sugar | N-acetyl-D-galactosamine |
| B antigen sugar | D-galactose |
| autologous donor | someone who donates their blood to be used for themselves later on |
| what lectin reacts with A1 | dolichos biflorus |
| what lectin can be used to type for H antigens | ulex europaeus |
| what illness is usually associated with acquired B antigens | GI diseases |
| IgG reacts at _______________ and IgM at _________ | IgG - 37C IgM - room temp |
| who discovered ABO system and when | Karl Landsteiner, early 1990's |
| in vitro vs vivo | vitro - test tube vivo - body |
| prozone vs postzone | pro - too much Ab post - too much Ag |
| what are the gene products of the A and B genes | transferase enzymes |
| universal donor and universal recipient | donor - O negative recipient - ABpositive |
| what blood group reacts strongest with anti-H | O |
| Anti-A serum is colored ________ and Anti-B _______ | Anti A - blue anti B - yellow |
| before saliva is tested for group specific substance it should be | boiled for 10 min to precipitate the protein |
| sensitization | when complement binds to a RBC as the initial stage of an Ag-Ab rx |
Created by:
kingsleya27