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Pharm 1.1

QuestionAnswer
Diphenhydramine is a antagonist of what receptor H1 receptor antagonist
Uses of diphenhydramine allergies, cold sx, vertigo/motion sickness, parkinsons, insomnia, urticaria
Adverse effects of diphenhydramine anticholinergic effects (dry mouth, tachycardia, urinary retention, hypotension, blurred vision)
Contraindications to diphenhydramine Under 2, narrow angle glaucoma, GI obstruction, acute asthma
Furosemide is a Loop diuretic, works faster via IV
Side effects of furosemide Hypokalemia, hypotension, dizziness, fatigue, tinnitus, ototoxic
Contraindications to furosemide Severe fluid/electrolyte imbalances, anuria, hepatic coma
Interactions with furosemide Amphotericin B, corticosteroids, can cause hypokalemia
what does furosemide do to insulin? Diminished the hypoglycemic effects of insulin
What labs can furosemide increase? BUN, serum amylase, cholesterol, triglyceride, serum electrolytes
Hawthorn and ginseng effects on furosemide hawthorn can cause hypotension, ginseng decreases effects of loop diuretic
what receptors does morphine bind? mu and kappa receptors.
When is morphine used? Relieves SOB and MI pain, and used preanesthesia
SE of morphine Constipation, N/V, dizziness, itching, CNS/resp depression
Contraindications to morphine Hepatic/renal issues, acute asthma, gi obstruction, early term delivery, caution with elderly.
What medicaitons should u be aware of with a patient on morphine? All downers, alcohol, antidepressants, kava, valerian, st johns wort
SE of naloxone increased BP, tremors, hyperventilation, N/V, drowsiness
When is naloxone administered? RR less than 10 for patients on opiates
Buprenoprhine; where does it produce agonism? delta and partial agonism at kappa receptors
Tramadol weaker opiod agonist and SNRI, weaker effect on mu and kappa.
What is buprenorphine used for? Buprenorphine is used for moderate pain and opiod weaning
SE of tramadol trad opiod, hepatotoxic, hypotension, hyponatremia
contraindications to tramadol children under 12, bowel obstruction, pregnancy,
What is CYP450 enzyme in liver responsible for metabolizing drugs
Created by: pharm3studysets
 

 



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