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Pharmacokinetics 165

Part 2

QuestionAnswer
Cardiac Output- Amount of blood pumped by the heart per minute
Regional Blood Flow- Amount of blood supplied to a specific organ or tissue
Drug Reservoirs- Drug accumulations that are bound to specific sites, such as plasma, fat tissue, and bone tissue
_______ also called bio-transformation, chemically changes a drug into a metabolite that can be excreted from the body Metabolism
The ________is primarily responsible for Metabolism Liver
Drugs usually undergo _________ one or both of the following types of chemical reactions in the liver: Oxidation or Conjugation
___ depends on dissolution properties of the dosage form, surface area, blood flow, concentration of drug at the site, acid-base properties surrounding the absorbing surface, lipophilicity of the drug, and compatibility with other chemicals or drugs Rate and Extent of Drug Absorption
Prior to ________, a drug must either undergo the absorption process or be administered by direct intravenous injection, thus bypassing the need for absorption Systemic Action
Disintegration and dissolution are generally considered to constitute the _______ of the Pharmacokinetic Process Beginning
Hydrolysis- Losing an e-
Reduction- Gaining an e-
Excretion is primarily accomplished by the ______ Kidneys
LIQUID DOSAGE FORM- SOLUTIONS
LIQUID DOSAGE FORM- EMULSIONS
LIQUID DOSAGE FORM- SUSPENSIONS
PARENTERAL DOSAGE FORM- SUBCUTANEOUS
PARENTERAL DOSAGE FORM- INTRAMUSCULAR
PARENTERAL DOSAGE FORM- INTRAVENOUS
SOLID DOSAGE FORM- TABLETS
SOLID DOSAGE FORM- CAPSULES
SOLID DOSAGE FORM- TROCHES
SOLID DOSAGE FORM- SUPPOSITORIES
Which dosage form is generally absorbed the fastest? Solutions
Which dosage form is generally absorbed the Slowest? Enteric-Coated Tablets
Pharmacology includes the understanding of all diagnostic, therapeutic, or adverse effects of medications in living systems True
Not all medications have a generic name False
Legend drugs do not require a prescription False
Radiopaque drugs are considered legend drugs True
The expiration date of a drug is considered one of the seven vital components of a valid prescription or order False
Controlled substances should be verified in count at the beginning and end of each shift True
Schedule C-V drugs are illegal for patient use in the United States False
The therapeutic index is the ratio of the median lethal dose to the median effective dose True
Imaging technologists are not required to place informed consent forms in the patient’s chart False
A prescription for a medication is a legal document admissible in a court of law True
Manufacturers pay to have their drugs listed in the Physician’s Desk Reference (PDR) True
________ is the random movement of a substance from a region of higher concentration to a region of lower concentration until equilibrium is established at the membrane. The majority of drugs are transported by this mechanism Passive Diffusion
______ is conducted by “carriers” that form complexes with drug molecules on one surface of the membrane, carry them through the membrane, and then let them go. Active transport is usually more rapid than passive diffusion. Active Transport
The ________ do not readily enter cells and therefore require active transport Ionic Forms of most Drugs
Created by: user-2016295
 

 



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