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Pharmacokinetics 165
Part 2
| Question | Answer |
|---|---|
| Cardiac Output- | Amount of blood pumped by the heart per minute |
| Regional Blood Flow- | Amount of blood supplied to a specific organ or tissue |
| Drug Reservoirs- | Drug accumulations that are bound to specific sites, such as plasma, fat tissue, and bone tissue |
| _______ also called bio-transformation, chemically changes a drug into a metabolite that can be excreted from the body | Metabolism |
| The ________is primarily responsible for Metabolism | Liver |
| Drugs usually undergo _________ one or both of the following types of chemical reactions in the liver: | Oxidation or Conjugation |
| ___ depends on dissolution properties of the dosage form, surface area, blood flow, concentration of drug at the site, acid-base properties surrounding the absorbing surface, lipophilicity of the drug, and compatibility with other chemicals or drugs | Rate and Extent of Drug Absorption |
| Prior to ________, a drug must either undergo the absorption process or be administered by direct intravenous injection, thus bypassing the need for absorption | Systemic Action |
| Disintegration and dissolution are generally considered to constitute the _______ of the Pharmacokinetic Process | Beginning |
| Hydrolysis- | Losing an e- |
| Reduction- | Gaining an e- |
| Excretion is primarily accomplished by the ______ | Kidneys |
| LIQUID DOSAGE FORM- | SOLUTIONS |
| LIQUID DOSAGE FORM- | EMULSIONS |
| LIQUID DOSAGE FORM- | SUSPENSIONS |
| PARENTERAL DOSAGE FORM- | SUBCUTANEOUS |
| PARENTERAL DOSAGE FORM- | INTRAMUSCULAR |
| PARENTERAL DOSAGE FORM- | INTRAVENOUS |
| SOLID DOSAGE FORM- | TABLETS |
| SOLID DOSAGE FORM- | CAPSULES |
| SOLID DOSAGE FORM- | TROCHES |
| SOLID DOSAGE FORM- | SUPPOSITORIES |
| Which dosage form is generally absorbed the fastest? | Solutions |
| Which dosage form is generally absorbed the Slowest? | Enteric-Coated Tablets |
| Pharmacology includes the understanding of all diagnostic, therapeutic, or adverse effects of medications in living systems | True |
| Not all medications have a generic name | False |
| Legend drugs do not require a prescription | False |
| Radiopaque drugs are considered legend drugs | True |
| The expiration date of a drug is considered one of the seven vital components of a valid prescription or order | False |
| Controlled substances should be verified in count at the beginning and end of each shift | True |
| Schedule C-V drugs are illegal for patient use in the United States | False |
| The therapeutic index is the ratio of the median lethal dose to the median effective dose | True |
| Imaging technologists are not required to place informed consent forms in the patient’s chart | False |
| A prescription for a medication is a legal document admissible in a court of law | True |
| Manufacturers pay to have their drugs listed in the Physician’s Desk Reference (PDR) | True |
| ________ is the random movement of a substance from a region of higher concentration to a region of lower concentration until equilibrium is established at the membrane. The majority of drugs are transported by this mechanism | Passive Diffusion |
| ______ is conducted by “carriers” that form complexes with drug molecules on one surface of the membrane, carry them through the membrane, and then let them go. Active transport is usually more rapid than passive diffusion. | Active Transport |
| The ________ do not readily enter cells and therefore require active transport | Ionic Forms of most Drugs |