click below
click below
Normal Size Small Size show me how
Ca blockers
| Question | Answer |
|---|---|
| Diltiazem = 3 negatives? | * Negative chronotrope → ↓ heart rate * Negative dromotrope → ↓ AV-node conduction * Negative inotrope → ↓ contractility That’s why non-dihydropyridine CCBs (diltiazem and verapamil) are generally avoided in HFrEF. |
| Amlodipine, Nifedipine, Nicardipine — think VESSELS 🩸 | These primarily cause arterial vasodilation. Vasodilation → ↓ SVR → ↓ afterload → ↓ BP They don’t significantly slow AV-node conduction like diltiazem/verapamil. |
| Digoxin | 1. Negative dromotrope → slows conduction through the AV node → ↓ ventricular rate. 2. Positive inotrope → ↑ cardiac contractility. |
| Chronotropy = RATE | Negative chronotrope → ↓ HR |
| Diltizem is what kind of inotrope | Diltiazem → ↓ SA rate (negative chronotropy) Diltiazem → ↓ AV conduction (negative dromotropy) Diltiazem → ↓ contractility (negative inotropy) |
| Adenosine is used for? | stable, regular, narrow-complex tachycardia (SVT). |
| What dose of adenosine is to be administered? | Dose: 6 mg rapid IV push → rapid saline flush If unsuccessful → 12 mg May repeat 12 mg if needed. Why rapid? Adenosine’s half-life is less than 10 seconds. It needs to reach the heart quickly. |
| What is Synchronized cardioversion used for? | Regular + narrow + stable → adenosine |
| Can you give nitroglycerin to pts with right ventricular infarction | No! be very cautious with nitroglycerin. Nitro → venodilation → ↓ preload → an already underfilled LV gets even less blood → severe hypotension. |
| Hemodynamics | CVP = RIGHT PAWP = LEFT CI = FLOW SVR = SQUEEZE of the vessels |
| septic shock s:s | CVP 3 ↓ PAWP 5 ↓ CI 4.8 ↑ SVR 500 ↓↓↓ |
| Biggest clue of septic shock? | Look at the strongest clue: 🔥 SVR 500 = VERY LOW In early (“warm”) septic shock, inflammatory mediators cause massive vasodilation. Vasodilation → ↓↓↓ SVR → hypotension ⭐ Hallmark of septic shock |
| hypovolemic shock s/s | Hypovolemic: ↓ CVP, ↓ PAWP, ↓ CI, ↑ SVR 🧠 Hypovolemic = tank is too EMPTY. |