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Ca blockers

QuestionAnswer
Diltiazem = 3 negatives? * Negative chronotrope → ↓ heart rate * Negative dromotrope → ↓ AV-node conduction * Negative inotrope → ↓ contractility That’s why non-dihydropyridine CCBs (diltiazem and verapamil) are generally avoided in HFrEF.
Amlodipine, Nifedipine, Nicardipine — think VESSELS 🩸 These primarily cause arterial vasodilation. Vasodilation → ↓ SVR → ↓ afterload → ↓ BP They don’t significantly slow AV-node conduction like diltiazem/verapamil.
Digoxin 1. Negative dromotrope → slows conduction through the AV node → ↓ ventricular rate. 2. Positive inotrope → ↑ cardiac contractility.
Chronotropy = RATE Negative chronotrope → ↓ HR
Diltizem is what kind of inotrope Diltiazem → ↓ SA rate (negative chronotropy) Diltiazem → ↓ AV conduction (negative dromotropy) Diltiazem → ↓ contractility (negative inotropy)
Adenosine is used for? stable, regular, narrow-complex tachycardia (SVT).
What dose of adenosine is to be administered? Dose: 6 mg rapid IV push → rapid saline flush If unsuccessful → 12 mg May repeat 12 mg if needed. Why rapid? Adenosine’s half-life is less than 10 seconds. It needs to reach the heart quickly.
What is Synchronized cardioversion used for? Regular + narrow + stable → adenosine
Can you give nitroglycerin to pts with right ventricular infarction No! be very cautious with nitroglycerin. Nitro → venodilation → ↓ preload → an already underfilled LV gets even less blood → severe hypotension.
Hemodynamics CVP = RIGHT PAWP = LEFT CI = FLOW SVR = SQUEEZE of the vessels
septic shock s:s CVP 3 ↓ PAWP 5 ↓ CI 4.8 ↑ SVR 500 ↓↓↓
Biggest clue of septic shock? Look at the strongest clue: 🔥 SVR 500 = VERY LOW In early (“warm”) septic shock, inflammatory mediators cause massive vasodilation. Vasodilation → ↓↓↓ SVR → hypotension ⭐ Hallmark of septic shock
hypovolemic shock s/s Hypovolemic: ↓ CVP, ↓ PAWP, ↓ CI, ↑ SVR 🧠 Hypovolemic = tank is too EMPTY.
Created by: Remarkable RN
 

 



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