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Cells and Tissues

Anatomy

TermDefinition
Cells Basic Structural and functional units of all living organisms, adult humans have 75 trillion cells with 200 different types
Somatic Cells Body cells
Germ Cells sex cells
Light Microscopy Visible light passes through a stained sample cell
Transmission Electron Microscopy Beam of electrons passes through a thin slice of specimen, creates a 2D image
Scanning Electron Microscopy Beam of electron bounces off surface of cell, creating a 3D image
Characteristics of living things organization, metabolism, growth and development, responsiveness, adaptation, regulation/homeostasis, reproduction
Anabolic Metabolism Building up
Catabolic Metabolism Breaking down
Functional category: Covering Protect outer surface of body, epithelial/epidermal skin cells
Functional category: Lining regulate nutrient movement into body tissues, epithelial cells in small intestine
Functional category: Connection/attachment Form ligaments or tendons, collagen (protein) fibers from fibroblasts
Ligaments Bone to bone attachment
Tendons Bone to muscle attachment
Functional category: Movement move skeleton, skeletal and cardiac muscle cells
Functional category: Communication send information between regions of the brain and spinal cord, neurons
Functional category: Defense Produce antibodies to target antigens or invading cells, lymphocytes
Functional category: Storage Store carbohydrate nutrients as glycogen, adipocytes storing lipid reserves, hepatocytes
Functional category: Reproduction produce a new individual, sperm and oocyte cells, bone marrow stem cells producing new blood cells
Prototypical Cell plasma membrane, cytoplasm, nucleus
Cytosol Fluid part of cytoplasm
Inclusions substances that are being stored in cells like melanin, glycogen and skeletal muscle cells
Organelles Membrane bound and non membrane bound
Plasma membrane can have tissue specific names, composed of mainly lipids and proteins in combination with carbohydrates to function as a selectively permeable membrane
Lipid componet 50 percent of membrane
Phospholipids 70 percent of lipids, in a bilayer with hydrophilic head and hydrophobic tail
Cholesterol 20 percent of lipids, a steroid type, scattered throughout bilayer, creates strength and stability
Glycolipids 5-10 percent of lipids, the outer part of membrane, part of glycocalyx
Protein Components 50 percent of membrane
Integral/Intrinsic Proteins embedded within and throughout bilayer, membrane channels allow some substances to pass through, receptors are binding sites and glycoproteins are a part of glycocalyx. Can function as enzyme
Peripheral/Extrinsic Proteins attached to internal or external surface of membrane, more soluble. Can function as enzyme.
Carbohydrate Componets/Glycocalyx functions in communication, cell-cell recognition and intracellular adhesion
Intracellular Fluid cytosol part of cytoplasm
Extracellular Fluid interstitial fluid, plasma in blood vessels, lymph in lymphatic vessels
Selective Permeability Factors Molecule size, concentration gradient, ionic charge, lipid solubility, transport proteins
Inclusions chemical substances that cells store temporarily
Glycogen storage unit of glucose in liver and skeletal muscle cells
Lipid Droplets triglyceride molecule accumulation in adipocytes
Melanin in skin, hair, and eyes, protects from suns UV light
Lipofuscin brown-yellow pigment associated with nerve cell bodies, aka the aging pigment
Rough ER continuous with nuclear envelope, has cisternae with ribosomes attached to cytoplasm side of membrane.
Cisternae flattened membraneous sacs that rough ER consists of
Smooth ER continuous with rough ER, no ribosomes, has interconnected branches of tubules, involved with synthesis, transport, storage of lipids, metabolism of carbohydrates and detoxification of drugs/alcohol
Golgi Apparatus receives and modifies proteins from ER, sorting and packing materials destined for the plasma membrane or for lysosomes. Has cisternae. Recieving (cis-face) region, and shipping (trans-face) regions. Can pinch of vesicles
Membrane-bound organelles: Lysosomes Membrane sacs generated by golgi apparatus, have enzymes that digest material brought into cell, break down damaged organelles, and can digest cell itself
Endocytosis active transport bringing in material by having the membrane fold in upon itself, creating a vesicle
Autophagy breaking down damaged organelles
Autolysis Digestion of cell
Membrane-bound organelles: Peroxisomes membrane enclosed sacs formed my pinching off rough ER, smaller than lysosomes, they detoxify - making hydrogen peroxide into water, and breaking down fatty acids
Membrane-bound organelles: Mitochondria have a double membrane, with cristae folds increasing the surface area for ATP synthesis. Also has a matrix with circular mitochondrial DNA inside.
Matrix Internal fluid, contains mitochondrial DNA
Non-Membrane bound organelles: Ribosomes free and bound ribosomes, have a small and large subunit that create the functional ribosome
Free Ribosomes produce proteins for cellular use
Bound Ribosomes produce proteins that are incorporated into plasma membrane, exported from cell, or within lysosome
Non-membrane bound organelles: Cytoskeleton Microfilaments, intermediate filaments and microtubles
Microfilaments 7nm in diameter, actin protein, associated with terminal web, help maintain cell shape, muscle contraction and seperates cell during cell division
Intermediate Filaments 8-12nm in diameter, Keratin protein that helps maintain cell shape and associated with some cell-cell junctions
Microtubules Hollow tubules 25 nm in diameter, tubulin protein, radiates from the centrosome and are associated with mitotic spindle, help maintain cell shape and stabilizing organelles, associated with cilia and flagella. Are non permanent structures.
Non-Membrane bound organelles: centrosome and centrioles found near nucleus, with a matrix - microtubule organizing center supporting growth and elongation of microtubules in nondividing cells, a pair arranged perpendicularly. Made of 9 microtubule triplets arranged in a circle, replicated before cell division
Cell Extensions: Cilia alot on apical surfaces of cells that line tracts, such as respiratory tracts where they move mucus
Cell Extensions: Flagella similar to cilia, but longer and singular, such as a sperm tail
Cell Extensions: Microvilli Short extensions from plasma membrane, smaller than cilia w/ different internal structure, they are non motile and form a brush border, such as intestine lining to increase surface area for absorption
Internal Structure of Cell Extensions: Axoneme In cilia, has 9 doublets of microtubules peripherally and a central pair of microtubules
internal Structure of Cell Extensions: Basal Body Often at apical margin, has 9 triplets of microtubules at the edge of cell in cytoplasm
Nuclecus Has a nuclear envelope which separates cytoplasm from nucleoplasm, with ribosome bound to cytoplasmic side. Nuclear pores give openings and it also has nucleoli
Nucleoli Spherical, made of RNA and create ribosome subunits
Gene unit of nuclear DNA
Nucleotide building blocks of DNA molecules, consisting of a sugar molecule, phosphate molecule and a nitrogenous base
Chromatin Form of non dividing DNA and associated histone proteins
Chromosomes during cell division, these condensed structures are created from chromatin
Mitosis Cell division within body/somatic cells, create 2 daughter cells with identical number of chromosomes. Includes prophase, metaphase, anaphase and telophase
Meiosis Cell division of gametes
Cytokeinesis Division of cytoplasm at the end of mitosis
G0 Phase State where non-dividing cells reside
G1 Phase first gap phase where cells replicate/produce new organelles and proteins, centriole replication at the end of this phase
S Phase DNA synthesis phase
G2 Phase second gap phase where centriole replication is complete and organelles are still being replicated
Prophase Chromatin forms chromosomes, microtubules develop into spindle fibers and form mitotic spindles. Centrioles migrate to poles and nuclear envelope breaks down. Early and late prophase can be recognized.
Chromosome sister chromatids attached by a centromere
Metaphase replicated chromosomes line up along equatorial plate. Spindle fibers attach to centromere and chromosomes
Anaphase spindle fibers pull sister chromatids apart at centromere towards poles. A contractile ring of actin protein filaments begin to form a cleavage furrow. Early and late anaphase can be recognized
Telophase A new nuclear envelope forms around each set of chromosomes, chromosomes uncoil into chromatin, mitotic spindle dissapears, nucleoli reappear and the cleavage furrow deepens and the cytoplasm is divided
Created by: user-2044712
 

 



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