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APC2 Quiz 4

Endocrine 1

BrandGenericCategoryIndicationsEssential Knowledge
Fortamet, Glumetza metformin (PO) Biguanide Type 2 DM, PCOS Key Side Effects: diarrhea, nausea, vomiting, Vitamin B12 deficiency Other Notes: CI with eGFR <30; US Boxed Warnings: lactic acidosis
Januvia, Zituvio sitagliptin (PO) Dipeptidyl peptidase (DPP-4) inhibitor Type 2 DM Key Side Effects: nasopharyngitis
Jardiance empagliflozin (PO) Sodium-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) Type 2 DM, HF, CKD Key Side Effects: genital mycotic infections, UTI
Farxiga dapagliflozin (PO) Sodium-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) Type 2 DM, HF, CKD Key Side Effects: genital mycotic infections, UTI
Amaryl glimepiride (PO) Sulfonylurea Type 2 DM Key Side Effects: hypoglycemia, weight gain
Glucotrol, Glucotrol XL glipizide (PO) Sulfonylurea Type 2 DM Key Side Effects: hypoglycemia, weight gain
Actos pioglitazone (PO) Thiazolidinedione (TZD) Type 2 DM Key Side Effects: peripheral edema, weight gain, upper respiratory tract infection; increased risk of fractures and bladder cancer US Boxed Warnings: may exacerbate congestive heart failure and CI in NYHA Class III and IV
Trulicity dulaglutide (SQ) Glucagon-like peptide-1 (GLP-1) receptor agonist Type 2 DM Key Side Effects: nausea, vomiting, diarrhea, pancreatitis US Boxed Warning: may increase risk of thyroid c-cell tumor, CI in personal or family history of medullary thyroid cancer and in patients with multiple endocrine neoplasia syndrome type 2
Victoza, Saxenda liraglutide (SQ) Glucagon-like peptide-1 (GLP-1) receptor agonist Type 2 DM, chronic weight management Key Side Effects: nausea, vomiting, diarrhea, constipation, pancreatitis US Boxed Warning: may increase risk of thyroid c-cell tumor, CI in personal or family history of medullary thyroid cancer and in patients with multiple endocrine neoplasia syndrome type 2
SQ: Ozempic, Wegovy PO: Rybelsus semaglutide (PO, SQ) Glucagon-like peptide-1 (GLP-1) receptor agonist Type 2 DM, chronic weight management Key Side Effects: nausea, vomiting, diarrhea, constipation, pancreatitis US Boxed Warning: may increase risk of thyroid c-cell tumor, CI in personal or family history of medullary thyroid cancer and in patients with multiple endocrine neoplasia syndrome type 2
Mounjaro, Zepbound tirzepatide (SQ) Dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) agonist Type 2 DM, chronic weight management Key Side Effects: nausea, vomiting, diarrhea, constipation, increased heart rate, pancreatitis US Boxed Warning: may increase risk of thyroid c-cell tumor, CI in personal or family history of medullary thyroid cancer and in patients with multiple endocrine neoplasia syndrome type 2
Lantus, Toujeo, Basaglar insulin glargine (SQ) Insulin, long acting Type 1 DM, type 2 DM Key Side Effects: hypoglycemia, weight gain
Humulin N, Novolin N insulin NPH (SQ) (OTC) Insulin, intermediate acting Type 1 DM, type 2 DM Key Side Effects: hypoglycemia, weight gain
Novolog insulin aspart (SQ) Insulin, rapid acting Type 1 DM, type 2 DM Key Side Effects: hypoglycemia, weight gain
Humalog insulin lispro (SQ) Insulin, rapid acting Type 1 DM, type 2 DM Key Side Effects: hypoglycemia, weight gain
Humulin R, Novolin R insulin regular (SQ, IV) SQ: OTC Insulin, short-acting Type 1 DM, type 2 DM, DKA Key Side Effects: hypoglycemia, weight gain
Created by: Kaitlynyip
 

 



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