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APC1 Quiz 1
CNS I
| Brand | Generic | Category | Indicators | Essential Knowledge |
|---|---|---|---|---|
| Remeron | mirtazapine (PO) | Alpha2 antagonist | MDD (major depressive disorder) | Key Side Effects: drowsiness, weight gain, xerostomia, increased appetite, constipation US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults |
| Wellbutrin SR, Wellbutrin XL | bupropion (PO) | Norepinephrine-dopamine reuptake inhibitor | MDD | Key Side Effects: tachycardia, headache, agitation, dizziness, insomnia, weight loss, xerostomia US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults; serious neuropsychiatric reactions have occurred. Other Notes: use may increase risk of seizure (CI in patients with seizure disorder and/or eating disorders) |
| Strattera | atomoxetine (PO) | Selective norepinephrine reuptake inhibitor | ADHD | hypertension, tachycardia, headache, xerostomia, nausea, vomiting, constipation, decreased appetite, insomnia US Boxed Warnings: increased risk of suicidal ideation in children or adolescents Other notes: CI within 14 days of MAOI |
| Pristiq | desvenlafaxine (PO) | Serotonin-norepinephrine reuptake inhibitor (SNRI) | MDD | Key Side Effects: headache, xerostomia, nausea, vomiting constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other notes: CI within 14 days of MAOI, don't discontinue abruptly |
| Cymbalta | duloxetine (PO) | Serotonin-norepinephrine reuptake inhibitor (SNRI) | MDD, neuropathic pain | Key Side Effects: headache, xerostomia, nausea, vomiting constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other notes: CI within 14 days of MAOI, don't discontinue abruptly |
| Effexor XR | venlafaxine (PO) | Serotonin-norepinephrine reuptake inhibitor (SNRI) | MDD | Key Side Effects: headache, xerostomia, nausea, vomiting constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other notes: CI within 14 days of MAOI, don't discontinue abruptly |
| Celexa | citalopram (PO) | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key Side Effects: drowsiness, insomnia, nausea, vomiting, xerostomia, sexual dysfunction, headache, diaphoresis US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other notes: CI within 14 days of MAOI; do not discontinue abruptly (all except fluoxetine) |
| Prozac | fluoxetine (PO) | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key Side Effects: headache, xerostomia, nausea, vomiting constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other notes: CI within 14 days of MAOI, don't discontinue abruptly |
| Lexapro | escitalopram (PO) | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key Side Effects: headache, xerostomia, nausea, vomiting constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other notes: CI within 14 days of MAOI, don't discontinue abruptly |
| Paxil | paroxetine (PO) | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key Side Effects: headache, xerostomia, nausea, vomiting constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other notes: CI within 14 days of MAOI, don't discontinue abruptly |
| Zoloft | sertraline (PO) | Selective serotonin reuptake inhibitor (SSRI) | MDD | Key Side Effects: headache, xerostomia, nausea, vomiting constipation, decreased appetite, insomnia, diaphoresis, hypertension, sexual dysfunction US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other notes: CI within 14 days of MAOI, don't discontinue abruptly |
| Desyrel | trazodone (PO) | Serotonin reuptake inhibitor | Insomnia, MDD | Key Side Effects: sedation, headache, dizziness, xerostomia, nausea, priapism, US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents and young adults |
| Elavil | amitriptyline (PO) | Tricyclic antidepressant (TCA) | MDD, diabetic neuropathy, migraine prophylaxis | Key Side Effects: dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, xerostomia, blurred vision, constipation US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other Notes: CI within 14 days of MAOI; do not discontinue abruptly |
| Pamelor | nortriptyline (PO) | Tricyclic antidepressant (TCA) | MDD, diabetic neuropathy, migraine prophylaxis | Key Side Effects: dizziness, drowsiness, orthostatic hypotension, sexual dysfunction, xerostomia, blurred vision, constipation US Boxed Warning: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other Notes: CI within 14 days of MAOI; do not discontinue abruptly |
| Silenor | doxepin (PO) | Tricyclic antidepressant (TCA) | Insomnia | Key Side Effects: somnolence, sedation, nausea US Boxed Warnings: increased risk of suicidal thinking and behavior in children, adolescents, and young adults Other Notes: CI within 14 days of MAOI; do not discontinue abruptly |