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Week 7 Assignment

Week 7 Assignment: Study Stack Exam Review

QuestionAnswer
Late Effects Radiation-induced damage at the cellular level may lead to measurable somatic and hereditary damage in the living organism as a whole later in life.
Examples of measurable late biologic damage Cataracts  Leukemia  Genetic mutations
Epidemiology The incident rates at which these irradiation- related malignancies occur are determined by comparing the natural incidence of cancer occurring in a human population with the incidence of cancer occurring in an irradiated population.
Carcinogenesis Also known as tumorigenesis
Cancer most significant late stochastic effects caused by exposure to ionizing radiation.
Radiation dose response relationship is demonstrated graphically through a curve that maps the observed effects of radiation exposure in relation to the dose of radiation received.
The observed effects of radiation exposure may be the incidence of a disease, or it may be the severity of an effect.
The DR curve either linear (straight line) or nonlinear
Threshold a point at which a response or reaction to an increasing stimulation first occurs
Nonthreshold indicates that a radiation absorbed dose of any magnitude has the capability of producing a biologic effect.
LNT curve implies that the biologic response to ionizing radiation is directly proportional to the dose received
Somatic Effects (1 of 2) When living organisms that have been exposed to radiation sustain biologic damage, the effects of this exposure are classified as somatic (i.e., body) effects.
Late Somatic Effects Are consequences of radiation exposure that appear months or years after such exposure
Major Types of Late Effects Carcinogenesis  Cataractogenesis  Embryologic effects (birth defects
Cataractogenesis Result  Partial or complete loss of vision  Results of laboratory experiments with mice  Radiation-induced cataracts in humans follow a threshold, nonlinear dose–response relationship
Biologic effects ionizing radiation on future generations
Created by: robertye12
 

 



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