click below
click below
Normal Size Small Size show me how
DPT_NEURO_3
PARKINSON'S DISEASE
| Question | Answer |
|---|---|
| Neurodegenerative dso | Parkinson's dse |
| Parkinson's dse is a degeneration of | Substantia nigra |
| Neurotransmitters involved in Parkinson's dse | DEC. Dopamine INC. Acetylcholine |
| 4 cardinal signs of Parkinson's dse | TRAP Tremors Rigidity Akinisia / Bradykinisia Postural instability |
| Characteristic is rigidity of Parkinson's dse | Cogwheel/lead pipe |
| Type of tremor in Parkinson's dse | Resting |
| Pathognomic sign (?) of Parkinson's dse | Pin rolling |
| Characteristic of speech in Parkinson's dse | Slow monotonous |
| Parkinson's dse is diagnosed with | PE&Hx requiring greather than 2 cardinal signs |
| Findings in pts with Parkinson's dse during autopsy | Lewy bodies |
| Confirmatory test in Parkinson's dse | Reaponse to levodopa |
| Intervention to improve mobility in terms of walking | Rock side-by-side, forward-backward Take big steps |
| Would you recommend exercise in Parkinson's dse | Yes |
| Best exercise overall for Parkinson's dse | Walking |
| Best exercise in Parkinson's dse to prevent fall | Tai chi |
| Nsg intervention in Parkinson's dse in terms of daily living particular;y elimination | Elevated toilet seat -> prevents flexion of hips & legs |
| Nutrition problem in Parkinson's dse | Aspiration |
| Intervention for aspiration in Parkinson's dse | Thick fluids, sit upright, small bites |
| Clothing type for Parkinson's dse | Velcro instead of buttons |
| What to advise to patients with Parkinson's dse when walking to prevent fall | Lift feet instead of dragging (shuffling gait) |
| Intervention for poor posture in Parkinson's dse | Firm mattress |
| DOC for Parkinson's dse | Carbidopa - Levodopa |
| Mainstay tx for Parkinson's dse | Carbidopa - Levodopa |
| What to avoid if taking Carbidopa - Levodopa | B6 / Pyridoxine , protein-rich |
| When should Carbidopa - Levodopa be taken | Before breakfast |
| Patient taking Carbidopa - Levodopa is experiencing dyskinesia (involuntary jerky mov't), what is the priority | Dose adjustment |
| Phenomenon experienced if taken Carbidopa - Levodopa | On/off phenomenon |
| side effects in Carbidopa - Levodopa in terms of elimination | Dark urine / sweat which may stain clothing |
| Drug for parkinson's dse which DEC. Acetylcholine and INC. Dopamine | Anti cholinergic |
| Drug for parkinson's dse effective for tremors and rigidity | Anticholinergic |
| Suffixes for Anticholinergic | -tropine ; trinexyphenidyl |
| Anticholinergic is C/I to | BPH, glaucoma |
| S/E of Anticholinergic | Sympa effects |
| Drug for Parkinson's specifically designed to extend the effectiveness of carbidopa/levodopa. | COMT inhibitors |
| Drug for Parkinson's to prevent wearing off / on or off phenomenon | COMT inhibitors |
| Suffix for COMT inhibitors | -pone |
| Drug for Parkinson's that mimics dopamine | Dopamine agonists |
| Dopamine agonists example | Pramipexole, ropinirole, amantadine |