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Pharmacology
Chapter 26
| Question | Answer |
|---|---|
| The process that stops bleeding is HEMOSTASIS | |
| Doesn't have the ability to clot HEMOPHILIA | |
| Coagulation means clot | True |
| Body ensures that we do not bleed out | True |
| Lack of oxygen ISCHEMIA | |
| Cause tissue death ISCHEMIA | |
| A blood clot THROMBUS | |
| A traveling clot EMBOLUS | |
| Clot breakdown is FIBRINOLYSIS | |
| Thrombocyte is platelets | True |
| Fibrin is CLOT | |
| Lysis is BREAKDOWN | |
| INR measures BLOOD CLOTTING TIME | |
| Coagulation cascade final results are FORMATION OF BLOOD CLOT | |
| Fibrinolytic system is Plasminogen converts to Plasmin | True |
| Plasmin is the liquid in our blood | True |
| Plasmin breaks down FIBRIN | True |
| Plasmin makes sure Fibrin does not get too big | True |
| Body ensures that we do not bleed out | True |
| Balance between clotting and clot breakdown is critical | True |
| Anticoagulants is a blood thinner but do not breakdown clots | |
| Anticoagulants are given for high risk of blood clotting | True |
| Heparin is blood thinner medication that is high risk and short term | True |
| Heparin is usually given in the hospital intravenous route and is unfragmented every 6 hours | True |
| What does aPTT stand for | Activated Partial Thromboplastin Time |
| aPTT means trying to keep a range | True |
| Injection medication can be given at home and is for long term use | Enoxaparin |
| Is processed in the body differently whereas labs are not needed | Enoxaparin |
| Medication is given for abdominal surgery's and immobile situations | Enoxaparin |
| Heparin inhibits Factor IIa (thrombin) and Factor Xa | True |
| Vitamin K is an antidote for | Warfarin |
| Warfarin Coumadin blocks clotting factors (hint 1972) | X, IX, VII, II |
| Lab monitoring for Warfarin/ Coumadin is | PT/INR |
| Normal INR is | 1.0 |
| Therapeutic INR is | 2.0 less than or equal to INR less than or equal to 3.5 |
| Heparin antidote is Protamine Sulfate | True |
| Dabigatran antidote is Idarucizumab | True |
| Xa Inhibitors antidote is Andexxa | True |
| Protamine reverses | Heparin |
| Vitamin K reverses | Warfarin |
| Major Adverse Effects are gum bleeding blood in stool (melena) blood in urine hematuria | |
| Melena is blood in the stool | True |
| Little purplish and bluish bruises everywhere (too much bleeding) is called Petechia | True |
| Thrombocytopenia is blood platelet count | True |
| HIT stands for Heparin- Induced Thrombocytopenia | True |
| Type I of HIT is platelets that have moved away from the site of injury | True |
| Type I is mild and continue therapy | True |
| Type II of HIT can be dangerous, platelets drop >50%, and stops heparin immediately | True |
Created by:
Daarina Jones