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631 Top Drugs Exam 2

Generic BrandCommon UseClassCI and WBBW
Acyclovir Zovirax Herpes simplex infection Antiviral None
Nirmatrelvir and Ritonavir Paxlovid COVID-19 Antiviral Significant drug interactions (this drug is a stong CYP3A inhibitor)
Valacyclovir Valtrex Herpes zoster, herpes labialis Nucleoside analogue None
Carvedilol Coreg Heart failure, Hypertension Beta adrenergic blocker - noncardioselective and alpha-1 adrenergic blocker bradycardia, heart block,heart failure None
Chlorthalidone Thalitone Hypertension Diuretic None
Clopidogrel Plavix Acute coronary syndrome, Myocardial infarction prevention, Stroke prevention Platelet activation and aggregation inhibitor bleeding risk Diminished antiplatelet effect in CYP2C19 poor metabolizers
Diltiazem Cardizem, Tiazac Angina, Hypertension Calcium channel blocker AV block, systolic BP <90, heart failure None
Doxazosin Cardura Hypertension, BPH Alpha adrenergic agonist None
Enalapril Vasotec Hypertension, Heart failure Angiotensin converting enzyme (ACE) inhibitor pregnancy, hx of angioedema Fetal toxicity
Furosemide Lasix Edema, Heart failure Loop diuretic Anuria, severe electrolyte imbalance Fluid & electrolyte depletion
Hydralazine Apresoline Hypertension, Heart failure Vasodilator None
Irbesartan Avapro Hypertension Angiotensin II receptor blocker (ARB) pregnancy Fetal toxicity
Isosorbide Dinitrate Isordil Angina Nitrate None
Isosorbide Mononitrate Ismo, Imdur Angina Nitrate None
Lisinopril Zestril, Prinivil Hypertension, Heart failure Angiotensin converting enzyme (ACE) inhibitor pregnancy, hx of angioedema Fetal toxicity
Lisinopril + Hydrochlorothiazide Zestoretic Hypertension, Heart failure Angiotensin converting enzyme (ACE) inhibitor + thiazide diuretic pregnancy, hx of angioedema Fetal toxicity
Losartan Cozaar Hypertension, Heart failure Angiotensin II receptor blocker (ARB) pregnancy Fetal toxicity
Losartan + hydrochlorothiazide Hyzaar Hypertension, Heart failure Angiotensin II receptor blocker (ARB) + thiazide diuretic pregnancy Fetal toxicity
Metoprolol Succinate Toprol XL Angina, Hypertension Beta adrenergic blocker bradycardia, heart block,heart failure None
Metoprolol Tartrate Lopressor Myocardial infarction Beta adrenergic blocker bradycardia, heart block,heart failure None
Nebivolol Bystolic Hypertension Beta 1 selective blocker heart failure, AV block None
Nifedipine Procardia, Adalat CC Hypertension Calcium channel blocker None
Olmesartan Benicar Hypertension Angiotensin II receptor blocker (ARB) pregnancy Fetal toxicity
Potassium Chloride Micro-K, Klor-Con Hypokalemia Essential mineral None
Propranolol Inderal Angina, Hypertension Beta adrenergic blocker bradycardia, heart block,heart failure None
Rivaroxaban Xarelto Stroke, Deep vein thrombosis Factor Xa inhibitor anticoagulant bleeding risk Increased throbotic event and stroke risk when DC'd early; Epidural/spinal hematoma risk
Sacubitril + Valsartan Entresto CHF Neprilysin Inhibitor + Angiotensin II receptor blocker (ARB) pregnancy Fetal toxicity
Telmisartan Micardis Hypertension Angiotensin II receptor blocker (ARB) pregnancy Fetal toxicity
Valsartan Diovan Hypertension, Heart Failure Angiotensin II receptor blocker (ARB) pregnancy Fetal toxicity
Verapamil Calan, Verelan Hypertension Calcium channel blocker AV block, systolic BP <90, heart failure None
Warfarin Coumadin Venous thromboemolism, Pulmonary embolism Vitamin K antagonist anticoagulant bleeding risk, pregnancy Major or fatal bleeding risk
Clobetasol Clobex Inflammation, Pruritus Corticosteroid None
Tretinoin Retin-A Acne Retinoid None
Calcium Carbonate TUMS Antacid, Electrolyte Supplement Antacid, Electrolyte Supplement None
Folic Acid Anemia, Dietary supplement Vitamin None
Magnesium Salts Mag-Ox Magnesium deficiency Antacid, Electrolyte Supplement None
Alendronate Fosamax Osteoporosis Bisphosphonate caution in pts with espophageal issues (ensure tablet is swallowed) None
Dulaglutide Trulicity Diabetes mellitus type 2 Glucagon-like peptide-1 (GLP-1) receptor agonist medullary thyroid cancer, multiple endocrine neoplasia syndrome, type 1 DM Risk of thyroid cancer
Estradiol Estrace Menopause Estrogen Risk of endometrial cancer
Ethinyl estradiol + Drospirenone Yaz, Yasmin Oral contraception Estrogen + Progestin risk of thromboembolism and cancer Smoking & cardiovascular risk, especially in patients >35
Ethinyl Estradiol + Etonogestrel NuvaRing Oral contraception Progestin + Estrogen risk of thromboembolism and cancer Smoking & cardiovascular risk, especially in patients >35
Ethinyl Estradiol + Levonorgestrel Lutera, Trivora Oral contraception Estrogen + Progestin risk of thromboembolism and cancer Smoking & cardiovascular risk, especially in patients >35
Ethinyl estradiol + Norethindrone Loestrin Oral contraception Estrogen + Progestin risk of thromboembolism and cancer Smoking & cardiovascular risk, especially in patients >35
Ethinyl estradiol + Norgestimate Estarylla Oral contraception Estrogen + Progestin risk of thromboembolism and cancer Smoking & cardiovascular risk, especially in patients >35
Glimepiride Amaryl Diabetes mellitus type 2 Sulfonylurea hypoglycemia risk None
Glipizide Glucotrol Diabetes mellitus type 2 Sulfonylurea hypoglycemia risk None
Insulin Aspart Novolog Diabetes mellitus Insulin - rapid acting hypoglycemia risk None
Insulin Degludec Tresiba Diabetes mellitus Insulin - long acting hypoglycemia risk, not to be used in insulin pump None
Insulin Glargine Lantus, Lantus SoloStar, Basaglar Diabetes mellitus Insulin - long acting hypoglycemia risk, not to be used in insulin pump None
Insulin Isophane Humulin N, Novolin N Diabetes mellitus Insulin - intermediate acting hypoglycemia risk, not to be used in insulin pump None
Insulin Lispro Humalog Diabetes mellitus Insulin - rapid acting hypoglycemia risk None
Levothyroxine Synthroid, Levoxyl Hypothyroidism Thyroid hormone Not to be used for weight loss
Metformin Glucophage Diabetes mellitus type 2 Biguanide + Dipeptyl Peptidase 4 (DPP-4) Inhibitor hx of lactic acisosis, renal dysfunction, dehydration Lactic acidosis
Norethindrone Ortho Micronor, Errin, Heather Oral contraception Progestin-only contraception Cigarette smoking increases risk of MI
Pioglitazone Actos Diabetes mellitus type 2 Thiazolidinedione CHF, type 1 diabetes, not for use in children Congestive heart failure
Progesterone Prometrium Endometrial Hyperplasia Progestin hypersensitivity to peanuts (oil in caps) None
Semaglutide Ozempic, Rybelsus Diabetes mellitus type 2 Glucagon-like peptide-1 (GLP-1) receptor agonist medullary thyroid cancer, multiple endocrine neoplasia syndrome, type 1 DM Risk of thyroid cancer
Sitagliptin Januvia Diabetes mellitus type 2 Dipeptidyl peptidase-4 (DPP-4) inhibitor type 1 DM None
Testosterone Depo-Testosterone, Androderm, Androgel Pump Male hypogonadism Androgen breast & prostate cancer, uncontrolled HTN Secondary exposure to testosterone (topical formulations) - advise caution
Thyroid Armour Thyroid, NP Thyroid Hypothyroidism Thyroid hormone Not to be used for weight loss
Tirzepatide Mounjaro, Zepbound Diabetes mellitus type 2, obesity-Weight management/sleep apnea Glucose-dependent insulinotropic polypeptide (GIP), Glucagon-like peptide-1 (GLP-1) receptor agonist medullary thyroid cancer, multiple endocrine neoplasia syndrome, type 1 DM Risk of thyroid cancer
Dapagliflozin Farxiga CKD, DM, HF Sodium-Glucose Cotransporter 2 (SGLT2) inhibitor pregnancy, renal dz None
Empagliflozin Jardiance CKD, DM, HF Sodium-Glucose Cotransporter 2 (SGLT2) inhibitor pregnancy, renal dz None
Dicyclomine Bentyl Irritable bowel syndrome Anticholinergic, Antispasmodic None
Docusate Colace Constipation Stool softener None
Linaclotide Linzess Constipation Guanylate Cyclase-C Agonist Not for use in children <2 years old Not for use in children <2 years old
Ondansetron Zofran Nausea, Vomiting Serotonin 5-HT3 receptor antagonist May increase risk of QT prolongation None
Polyethylene Glycol 3350 Miralax, Glycolax Constipation, Bowel evacuation Osmotic laxative None
Ferrous Sulfate Anemia, Dietary supplement Essential mineral None
Adalimumab Humira Rheumatoid arthritis, Psoriasis, Crohn's disease, Ulcerative colitis Antirheumatic, Monoclonal antibody, TNF blocking agent Serious risk of infection & malignancy
Budesonide Uceris, Entocort EC Ulcerative colitis, Crohn's dz Corticosteroid None
Hydrocortisone Cortizone 10, Solu-Corlef Rash, Inflammation Corticosteroid None
Hydroxychloroquine Plaquenil Rheumatoid arthritis, Malaria Anti-malarial, Immune modulator QT Prolongation Risk None
Methotrexate Trexall, Rheumatrex Rheumatoid arthritis, Psoriasis, Crohn's disease, Ulcerative colitis, Cancers Antimetabolite pregnancy, pts with renal, hepatic, or pulmonary dysfunction, myelosuppression MANY boxed warning, including: Fetal toxicity, pulmonary toxicity, hepatotoxicity, GI toxicity, risk of lymphoma, and more
Methylprednisolone Medrol, Solu-Medrol Inflammation Glucocorticoid None
Prednisolone Allergies, Inflammation Corticosteroid None
Prednisone Allergies, Inflammation Corticosteroid None
Triamcinolone Aristocort, Kenolog Allergies, Inflammation, Asthma Corticosteriod None
Baclofen Lioresal Muscle spasms Muscle relaxant (central) None
Cyclobenzaprine Flexeril Muscle spasms Muscle relaxant (central) None
Methocarbamol Robaxin Musculoskeletal discomfort Muscle relaxant (central) None
Tizanidine Zanaflex Muscle spasms Alpha-2 adrenergic agonist QT Prolongation Risk None
Melatonin Insomnia Melatonin receptor agonist None
Phentermine Adipex-P, Fastin Obesity Sympathomimetic amine hx of cardiovascular dz, pregnancy, renal dysfunction, uncontrolled HTN None
Sumatriptan Imitrex Migraine Selective (5-HT1B/1D)serotonin receptor agonists Uncontrolled HTN, arrhythmia, cerebrovascular dz None
Anastrozole Arimidex Breast cancer Aromatase inhibitor pregnancy, pre-menopausal pts None
Dorzolamide Trusopt Glaucoma Carbonic Anhydrase Inhibitor None
Latanoprost Xalatan Glaucoma Prostaglandin analog None
Timolol Timoptic, Betimol Glaucoma Beta adrenergic blocker caution in pts with asthma, COPD, or heart disease None
Albuterol Ventolin, Proventil, ProAir Asthma Beta-2-adrenergic agonist None
Albuterol + ipratropium Duoneb (ipratropium + albuterol) Rx Asthma and COPd Beta-2-adrenergic agonist + muscarinic antagonists None
Benzonatate Tessalon Perles Cough Stretch receptor anesthestic None
Budesonide + Formoterol Symbicort Asthma, Chronic obstructive pulmonary disease (COPD) Corticosteroid + Long-acting beta-2 adrenergic agonist None
Fluticasone + Umeclidinium + Vilanterol Trelegy Ellipta Asthma, Chronic obstructive pulmonary disease (COPD) Corticosteroid + long-acting muscarinic antagonists + long-acting beta-2 adrenergic agonist None
Fluticasone + Vilanterol Breo Ellipta Asthma, Chronic obstructive pulmonary disease (COPD) Corticosteroid + long-acting beta-2 adrenergic agonist None
Tiotropium Spiriva HandiHaler Chronic obstructive pulmonary disease (COPD) Anticholinergic None
Fluticasone Flonase, Flonase HFA, Flovent (asthma) Allergies Corticosteroid None
Fluticasone + Salmeterol Advair Diskus Asthma, Chronic obstructive pulmonary disease (COPD) Corticosteroid + long-acting beta-2 adrenergic agonist None
Cholecalciferol Osteoporosis Stimulates bone mineralization None
Cyanocobalamin Vitamin B12 deficiency Coenzyme for various metabolic functions None
Ergocalciferol Osteoporosis Stimulates bone mineralization None
Created by: cakedo6
 

 



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