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Sterile Compounding
| Question | Answer |
|---|---|
| What is a HEPA filter? | High-Efficiency Particulate Air filter. Removes: 99.97% of particles ≥0.3 microns Creates ISO Class 5 air. |
| What is First Air? | The first clean air coming directly from the HEPA filter. Critical sites must always receive first air. Never block it. |
| What is a critical site? | Any sterile surface that must never be contaminated. Examples * needle * needle hub * syringe tip * ampule opening * vial stopper after disinfecting Never touch these. |
| What is a LAFW? | Laminar Air Flow Workbench: A sterile hood that produces ISO Class 5 air. Used for sterile compounding. |
| How does the horizontal hood do? | Air moves: Back ↓ Forward Toward technician. Used ONLY for: Nonhazardous medications. |
| How does the vertical hood do? | Air moves: Top ↓ Bottom Used for hazardous medications. |
| What does a Biological Safety Cabinet protect? | an enclosed, ventilated workspace used in laboratories to safely handle materials contaminated with (or potentially containing) infectious pathogens |
| What is a CVE? | Containment Ventilated Enclosure Often called a powder hood. Used when handling hazardous powders so they do not spread into the work environment. |
| What is a PEC? | Primary Engineering Control: Any device that creates ISO Class 5 air. Examples * LAFW * Biological Safety Cabinet * Compounding Aseptic Isolator (CAI) |
| What is a Compounding Aseptic Isolator (CAI)? | an enclosed, positive-pressure glovebox designed to prepare sterile, non-hazardous medications. |
| What is IPA? | 70% Isopropyl Alcohol... BECAUSE Water slows evaporation. This gives alcohol more time to kill microorganisms. 70% kills microbes better than 100%. |
| What is a clean room? | Highly controlled sterile environment. Contains the buffer room. |
| What is the anteroom? | The room before entering the sterile compounding area. Used for: - hand hygiene -Garbing = ALL your protective gear - Gowning = actually putting on the gown |
| What is the buffer room? | The actual sterile compounding room. Contains sterile hoods |