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clinchem endocrine

QuestionAnswer
endocrine system regulates and maintains various body functions by synthesizing and releasing hormones
endocrine glands secrete into the ECM and blood (ductless system)
The target of effector hormones is other _____________ tissues
neurohypophysis posterior pituitary
posterior pituitary hormones oxytocin and antidiuretic hormone
Releasing factors are produced by the ________________________ and secreted into the anterior pituitary hypothalamus
adenohypophysis anterior pituitary
prolactin stimulates milk production
The pituitary glands have been described as looking similar to: garbanzo beans
Hypersecretion of ___________________ during childhood may result in giantism growth hormone
the hypothalamus connects the CNS to the ___________ system endocrine
The target of tropic hormones are other _______________ glands
calcium reference range 8.6-10 mg/dL
what is the most important test for hypothyroidism? TSH
hypothyroid patients may also have anemia
3 chemical types of proteins 1. polypeptides 2. amino acid derivatives 3. steroids
anterior pituitary hormones FSH, LH, GH, ACTH, prolactin, TSH
pineal gland hormones melatonin and serotonin
adrenal medulla hormones epinephrine, norepinephrine, dopamine
what is the major glucocorticoid in humans? cortisol
what is the most important mineral corticoid aldosterone
cortisol is highest in the _____________ and lowest in the __________ morning; afternoon
growth hormone is highest in the evening
elevated GH causes .... decreased GH causes..... gigantism, acromegaly dwarfism, simmons
calcitonin is made in the thyroid gland
vanillylmandelic acid (VMA) comes from the metabolization of epinephrine and norepinephrine
dexamethasone suppression test documents the hypersecretion of adrenocortical hormones (cortisol)
thyroxine binding globulin protein carrier for thyroid hormones
transcortin protein carrier for cortisol
what is the primary active thyroid hormone in the blood T3
anterior pituitary hormone release is controlled by TRH, CRH, GnRH, GHRH
what is the most potent estrogen? estradiol
organs that secrete steroid hormones adrenal glands, gonads, placenta
what hormone is measured when pregnant HCG
mothers of babies with down syndrome have decreased estriol
what hormone is related to zollinger-ellison syndrome> gastrin
hyperparathyroidism increases______ and decreases ____ Ca++ ; P
symptoms of hyperthyroidism heat intolerance, flushed skin, palpitations, tachycardia, weight loss, restlessness, proptosis
2 important metabolites of catecholamines 1. Vanillylmandelic acid (VMA) 2. homovanillic acid (HMA)
cyclic AMP is activated by epinephrine, glucagon, TSH, LH and FSH, ADH and PTH
hydatidiform mole noncancerous tumor that develops from an abnormal fertilized egg
what surges before ovulation LH
what maintains pregnancy progesterone
in radioimmunoassay (RIA), the final gamma point is _________ proportional to the amount of target substance in the patient sample inversely
tropic hormone target is another endocrine gland
hormones function to maintain homeostasis, regulate growth and development, promote sexual maturity and reproduction, regulate energy produced and stabilize the metabolic rate, adjust stress, regulate the release of other hormones
what hormones are lipid soluble steroid and ionated hormones
what is the largest endocrine gland thyroid
graves disease autoimmune disease; body produces Ab to the thyroid causing a hyperthyroid reaction
addisons disease decreased ACTH and/or cortisol; failure to thrive, dehydration, weight loss, weakness, fatigue
cushings syndrome hypercortisol disease; increased ACTH; truncal obesity, buffalo hump, protein wasting, poor wound healing, hyperglycemia
cortisol has an anti-insulin effect, effects water and electrolyte balance, suppresses inflammatory and allergic reactions
cortisol is regulated by ACTH and CRH
pheochromatocytomas tumors of the adrenal medulla; causes and increase in catecholamines released
FSH works only with LH; causes estrogen production
hyperparathyroidism vs hyperparathyroidism hyper: elevated calcium --> kidney stones hypo: decreased calcium and PTH, increased P ; tetany and neuromuscular problems
hypothyroid hormone levels decreased T3 and T4, increased TSH
hashimotos autoimmune disease where body eventually stops producing T3 and T4 ; cold interolance, dry skin, weight gain, eyebrow loss
effector hormones effect non endocrine tissues
5 structural classes of hormones protein, glycoprotein, peptides, AA derivatives, steroids
Created by: kingsleya27
 

 



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