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Week 7

Gastrointestinal and hormones

Generic Brand Class Indications Side effects Counseling Contraindication BBW
Lubiprostone Amitiza chloride channel activator chronic idiopathic constipation Irritable bowel syndrome with constipation. Opioid induced constipation Nausea (take with food) Diarrhea, dyspnea shortly after dose Take with water. Swallow whole. Stop if severe diarrhea.
Metoclopramide Reglan Dopamine Antagonist Gastroparesis GERD (short term) Antimetic Extrapyramidal symptoms. Tardive dyskinesia. Limit use to <12 week Take 30 min before meals and at bedtime. Avoid long term use ( >12 week) Report involuntary movements immediately. GI obstruction, perforation or hemorrhage Tardive dyskinesia (long term use)
Phenazopyridine Pyridium Urinary tract analgesic symptomatic relief of urinary pain, burning, urgency Red-orange discoloration of urine. Not an antibiotic (relieves symptoms) Take after meals to reduce GI upset. Not an antibiotic Renal impairment
Polyethylene Glycol Golytely Hyperosmotic laxative Bowel preparation before colonoscopy. Constipation Large volume intake required. Nausea, bloating Drink rapidly as directed until stool is clear. Expect frequent water stools GI obstruction
Medroxyprogesterone Provera Progestin hormone Contraception, uterine bleeding Weight gain, mood changes , amenorrhea Avoid St. Johns wort during therapy. Report sign of blood clots (leg pain, chest pain) Undiagnosed vaginal bleeding. Known/suspected breast cancer. Pregnancy and liver disease cardiovascular disorders, Breast cancer, probable dementia.
Benztropine Cogentin Anticholinergic, antiparkinsonian Parkinsonism. drug induced extrapyramidal symptoms Anticholinergic effects( dry mouth, constipation, urinary retention) Heat intolerance Avoid in elderly Stay hydrated to manage constipation. Narrow angle glaucoma
Phenytoin Dilantin Hydantoin anticonvulsant Seizures Gingival hyperplasia. SJS/TEN. Hepatotoxicity Nystagmus Monitor drug levels. Maintain good oral hygiene Concurrent use of delavirdine. History of prior acute hepatotoxicity attributable to phenytoin. Sinus bradycardia, 2nd and 3rd degree heart block. Severe hypotension and arrhythmias with rapid IV administration.
Clobazam Onfi, Sympazan benzodiazepine CIV Seizures associated with Lennox-gastaut syndrome Serious dermatologic reaction. respiratory depression Avoid alcohol/opioid. May decrease the effectiveness of hormonal contraceptives and to use additional non- hormonal methods of contraception.
Created by: angelicap
 

 



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