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NAPLEX
acute & critical care
| Question | Answer |
|---|---|
| when is hyponatremia symptomatic? | when is reaches <120 |
| when can you use conivaptan and tolvaptan? | for hypotonic hypervolemic hyponatremia |
| what type of hyponatremia does SIADH causes? | hypotonic isovolemic (euvolemic) hyponatremia |
| what drug can be used off-label for hypotonic isovolemic (euvolemic) hyponatremia? | demeclocycline |
| what drugs to use in a patient with hypotonic hypovolemic hyponatremia? | IV hypertonic (3%) saline can be used in patients with severe symptoms or Na <120 |
| what is the goal of sodium correction per 24 hours? | 4-8 mEq/L |
| what is limit of sodium correction before causing ODS | correcting Na more rapidly than 12 mEq/L per 24 hours |
| what drug can reduce water diuresis and avoid over correction? | desmopressin |
| which arginine vasopressin receptor antagonist should not be used for more than 30 days? | oral tolvaptan |
| If a patient experiences hypokalemia and hypomagnesemia together, what do you correct first? | magnesium |
| what to give if Mg <1 | IV magnesium sulfate replacement |
| what to give if Mg >1 or <1.5 | PO magnesium oxide |
| when do you replace phosphorus with IV phosphorus | when PO4 is <1 |
| when do you use a slower infusion rate for IVIG? | in renal and CV disease |
| what is the BW with IVIG products? | acute renal dysfunction more likely with products stabilized with sucrose |
| what is the CI of using IVIG? | IgA deficiency |