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Week 6
| Genertic | Brand | Class | Indication | BBW | Side Effects | Counseling |
|---|---|---|---|---|---|---|
| Nirmatrelvir/ritonavir | Paxlovid | Antiviral; SAR-CoV-2 Main protease inhibitor | Treatment of mild to moderate COVID -19 (40kg and up) | Strong CYP3A4 | Dygeusia and diarrhea Hepatotoxicity | Timing, must be initiated within 5 days of symptoms onset |
| Fidaxomicin | Dificid | Macrolide | Clostridioides difficile associate diarrhea (CDAD) C-diff | Nausea, vomiting, abdominal pain and anemia | Acts locally in GI tract. it should be used for systemic infection. | |
| Gatifloxacin | zymaxid | Fluoroquinolone antibiotic | Bacterial conjunctivitis | Worsening of conjunctivitis, eye irritation, dysgeusia and eye pain | Avoid touching the applicator with finger or any other surface. | |
| Imiquimod | Zyclara | Immune response modifier | Actinic keratoses on the face or balding scalp. warts if external use. | Redness, scabbing, dryness. Flu-like symptoms, photosensitivity | once daily in 2 week cycle. 2 weeks on 2 weeks off | |
| Levofloxacin | Levaquin | Fluoroquinolone antibiotic | Bacterial infection | Severe AE: Tendinitis, tendon rupture Myasthenia Gravis | QT prolongation, c-diff, photosensitivity, aortic aneurysm/dissection | Do not take with antacids, multivitamins, products containing Ca, Mg, Al, Iron and Zn . Glucose monitoring |
| Moxifloxacin | Vigamox | Fluoroquinolone antibiotic ophthalmic | Bacterial conjunctivitis | conjunctivitis, decreased visual acuity, dry eye, ocular discomfort | Avoid touching the applicator with finger or any other surface. | |
| Mupirocin | Bactroban | Topical antibiotic | treatment for staph. aureus and strep pyogenes | Burning, stinging, pain or itching at the application site | Not used for eyes or on mucous membranes | |
| Nitazoxanide | Alinia | Antiprotozoal | Treatment of diarrhea caused by giardia lambila or cryptosporidium | Abdominal pain, diarrhea, headache and nausea. Urine discoloration | Administer with food. Shake prior to use | |
| Penicillin VK | Beta- lactam | gingivitis, pneumococcal infection like pneumococcal respiratory tract infection | C-diff associated diarrhea. ananphlylaxis | Complete full course. Report any rash or breathing difficulty. take on empty stomach 1 hour before a meal. | ||
| Metronidazole | Flagyl | Nitroimidazole antibiotic | Bacterial vaginosis C-diff infection | Potential carcinogenic risk | Disulfiram like reaction with alcohol. Metallic taste, peripheral neuropathy (long term use) | Avoid alcohol during and at least 48-72 hour after therapy . take with food |
| DTaP/Tdap | Adacel/Boostrix | Inactivated bacterial vaccine | Prevention of diphtheria | local injection reaction. fever | give every 10 years and during each pregnancy (27-36 weeks) | |
| Haemophilus | ActHIB/Hiberix | Inactivated bacterial vaccine | presentation of haemophilus influenza type b infection. | local injection reaction and Anorexia | given in infacny |