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RxPrep
HIV Medications
| Brand Name | Generic Name | Components | Role in Therapy | Clinical Pearls |
|---|---|---|---|---|
| Biktarvy | Bictegravir + Emtricitabine + Tenofovir Alafenamide | INSTI + 2 NRTIs | First-line ART for HIV treatment | Once daily pill |
| Cabenuva | Cabotegravir + Rilpirivine | INSTI + NNRTI | Replaces a stable ART regimen in patients with virologic suppression | IM monthly |
| Triumeq | Dolutegravir + Abacavir + Lamivudine | INSTI + 2 NRTIs | Contains abacavir | |
| Dovato | Dolutegravir + Lamivudine | INSTI + NRTI | First-line ART for HIV treatment | Do not use in treatment-naive patients if HIV RNA >500k copies/mL Once daily pill |
| Juluca | Dolutegravir + Rilpirivine | INSTI + NNRTI | Replaces a stable ART regimen in patients with virologic suppression | Take with food (rilpirivine) |
| Stribild | Elvitegravir + Cobicistat + Emtricitabine + TDF | INSTI + PK Booster + 2 NRTIs | Do not use if CrCl <70 Take with food (cobicistat) | |
| Genvoya | Elvitegravir + Cobicistat + Emtricitabine + TAF | INSTI + PK Booster + 2 NRTIs | Take with food (cobicistat) | |
| Delstrigo | Doravirine + Lamivudine + Tenofovir Disoproxil Fumarate | NNRTI + 2 NRTIs | ||
| Symfi, Symfi Lo | Efavirenz + Lamivudine + Tenofovir Disoproxil Fumarate | NNRTI + 2 NRTIs | Take on empty stomach (efavirenz) | |
| Complera | Rilpirivine + Emtricitabine + Tenofovir Disoproxil Fumarate | NNRTI + 2 NRTIs | Take with food (rilpirivine) | |
| Odefsey | Rilpirivine + Emtricitabine + Tenofovir Alafenamide | NNRTI + 2 NRTIs | Take with food (rilpirivine) | |
| Symtuza | Darunavir + Cobicistat + Emtricitabine + Tenofovir Alafenamide | PI + PK Booster + 2 NRTIs | Take with food (cobicistat). Do not start if CrCl <30 (TAF). | |
| Epzicom | Abacavir + Lamivudine | 2 NRTIs | Contains abacavir | |
| Descovy | Emtricitabine + Tenofovir Alafenamide | 2 NRTIs | First-line for PrEP | |
| Truvada | Emtricitabine + Tenofovir Disoproxil Fumarate | 2 NRTIs | First-line for PrEP; give with Tivicay or Isentress for PEP | |
| Cimduo | Lamivudine + Tenofovir Disoproxil Fumarate | 2 NRTIs | Do not use if CrCl <50 | |
| Combivir | Lamivudine + Zidovudine | 2 NRTIs | Twice daily pill | |
| Evotaz | Atazanavir + Cobicistat | PI + PK Booster | Take with food (cobicistat) | |
| Prezcobix | Darunavir + Cobicistat | PI + PK Booster | Take with food (cobicistat). Caution in sulfa allergy (darunavir) | |
| Apretude | Cabotegravir | INSTI | IM drug for PrEP | Monthly x 2 doses, then every 2 months |
| Tivicay | Dolutegravir | INSTI | ||
| Isentress | Raltegravir | INSTI | Twice daily pill | |
| Viread | Tenofovir Disoproxil Fumarate | NRTI | ||
| Vemlidy | Tenofovir Alafenamide | NRTI | Single-entity product for HBV | |
| Retrovir | Zidovudine | NRTI | Administered IV during L&D to prevent perinatal HIV transmission to the newborn | |
| Pifeltro | Doravirine | NNRTI | ||
| Reyataz | Atazanavir | PI | Needs acidic gut for absorption; hyperbilirubinemia | |
| Prezista | Darunavir | PI | Caution in sulfa allergy | |
| Norvir | Ritonavir | PK Booster | ||
| Tybost | Cobicistat | PK Booster | ||
| Zelzentry | Maraviroc | CCR5 Antagonist (blocks binding) | Must have tropism assay results before starting | |
| Rukobia | Fostemsavir | Attachment Inhibitor | ||
| Trogarzo (IV) | Ibalizumab-uiyk | Post-Attachment Inhibitor | ||
| Sunlenca (tab -> SC) | Lenacapavir | Capsid Inhibitor |