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QUANTEC YR3
| Question | Answer |
|---|---|
| Brain max and endpoint | Max <60Gy. Symptomatic necrosis |
| Brainstem max and endpoint | Max <54Gy. Necrosis/neuropathy |
| Brainstem vol | D1-10cc<= 59Gy |
| Optic nerve/chiasm | Max <55Gy. Optic neuropathy |
| Spinal cord and PRV | Spinal cord max 45-50Gy. PRV 48-55Gy. Myelopathy |
| Cochlea | Mean <=45Gy. Sensory-neural hearing loss |
| Parotid bilateral | Mean <=25Gy. Long term salivary function <25% |
| Parotid unilateral | Mean <=20Gy. Long term salivary function <25% |
| Pharyngeal constrictors | Mean <=50Gy. Symptomatic dysphagia and aspiration |
| Larynx goals | Max <66Gy (vocal dysfunction) Mean <50Gy (aspiration) Mean <44Gy (oedema) V50<27 (oedema) |
| Lung | V20<=30% (symptomatic pneumonitis) Mean 7Gy |
| Oesophagus | Mean <34Gy. Grade 3+ oesophagitis |
| Heart | Mean <26Gy, Pericarditis V25<10, Long term cardiac morality |
| Liver | Mean <30-32Gy (RILD) |
| Kidney (bi) | Mean <15-18Gy (clinical dysfunction) |
| Small bowel (loops) | V15<120cc (Grade 3+ toxicity) |
| Small bowel (cavity) | V45<195cc (Grade 3+ toxicity) |
| Rectum | V50<50 V60<35 V65<25 V70<20 V75<15 Grade 3+ toxicity |
| Bladder (bladder cancer) | Max <65Gy (Grade 3+ toxicity) |
| Bladder (prostate) | V65<50 V70<35 V75<25 V80<15 Grade 3+ toxicity |
| Penile bulb | Mean dose to 95% <50Gy D90<50Gy Severe erectile dysfunction |
| Oral Cavity | Mean <40Gy (grade 3+ mucositis) |
| Lenses | Max 5Gy (cataracts) |
| Acoustics | Mean <50Gy (SNHL) |
| TMJ | Max <70Gy (trismus) |
| Mandible | Mean <40Gy (ORN) |
| Heart (breast) | Mean <4Gy, V20<5 (long term cardiac mortality) |
| Spinal cord (breast) | Max 20Gy (myelopathy) |
| Rectall wall | V40<80 (grade 3+ toxicity) |
| Femoral heads | V30<50 V40<35 V44<5 (ORN) |
| chest wall, ribs, skin? | |
| hippocampus, temoral lobe? |