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ID 1

QuestionAnswer
which 2 antibiotic class have a synergistic energy that can be used for infective endocarditis aminoglycosides and beta-lactams
which abx are the cell membrane inhibitors? Polymyxin, daptomycin, telavancin, oritavancin
which abx are the folic acid synthesis inhibitors? sulfonamide, trimethorpim, dapsone
which ones are the cell wall inhibitors? beta-lactams, monobactams (aztreonam), vancomycin
MOA of metronidazole DNA/RNA inhibitors
MOA of macrolides? protein synthesis inhibitors
are aminoglycosides concentration-dependent or time-dependent? concentration-dependent
are beta-lactams concentration-dependent or time-dependent? time-dependent
which of the natural penicillins is not for IV use and can cause cardio-respiratory arrest and death? Penicillin G benzathine
what does augmentin and unasyn have a history of? cholestatic jaundice or hepatic dysfunction associated with previous use
what is the renal cutoff for using amoxicillin/clavulanate ER or the 875mg strength CrCI <30
brand name for penicillin G benzathine Bicillin L-A
do the antispahylocaccoal penicillins require renal dose adjustments? no
what to do if extravasation occurs with nafcillin? use cold packs and hyaluronidase injections
why is ampicillin PO rarely used? due to poor bioavailability
what drug can increase the levels of beta-lactams by interfering with renal excretion? probenecid
penicillin can increase the serum concentration of what drug? methotrexate
what does nafcillin and oxacillin do to warfarin/ they inhibit the anticoagulant effect of warfarin
what are the exceptions to using penicillins in a patient with a beta-lactam allergy? treatment of syphilis during pregnancy or in patients with poor adherence/follow up-desensitize and treat with penicillin G benzazthine
Created by: KaHerre12
 

 



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