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patho 1
| Question | Answer |
|---|---|
| atrophy | decrease in size |
| hypertrophy | increase in size |
| hyperplasia | increase in number of cells |
| metaplasia | replacement of adult cells |
| dysplasia | deranged cell growth of specific tissue |
| effects of lead on cells | inactivates enzymes, competes with calcium in bones and interferes with nerve transmission |
| what are free radicals? | highly reactive chemical species with an unpaired electron |
| hypoxic cell injury | deprives cell of oxygen and interrupts oxidative metabolism and the generation of ATP |
| apoptosis | programmed cell death |
| necrosis | cell death in an organ or tissues that is still part of a living person |
| gangrene | when a considerable mass of tissue undergoes necrosis |
| dry gangrene | affected tissue dries and shrinks, skin wrinkles and color deepens to brown/ black, spreads slowly |
| wet gangrene | affected area is cold, swollen and pulseless. skin is moist, black, and under tension. blebs form on the surface, liquefaction occurs and a foul odor is caused by bacteria. spreads rapidly |
| marfan sydrome | autosomal dominant connective tissue disorder manifested by changes in the skeleton, eyes, and cardiovascular system |
| neurofibromatosis (NF) | autosomal dominant condition involving neurogenic tumors that arise from schwann cells and other elements of the PNS |
| phenylketonuria (PKU) | autosomal recessive disorder caused by a deficiency of the liver enzyme phenylalanine hydroxylase |
| tay-sachs disease | autosomal recessive disorder that leads to toxic buildup of fatty substances in the brain and spinal cord |