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Period 1
| Conquistadors | 16th-century Spanish explorers, adventurers, and soldiers who led military expeditions into the Americas to conquer indigenous empires, secure vast territories for the Spanish Crown, and Acquire personal wealth |
| Bartolome De Las Casas | 16th-century Spanish Dominican priest, missionary, and former conquistador, became a leading advocate for the rights of Native Americans, criticized the harsh cruelties of the encomienda system and urged the Spanish monarchy to adopt more humane |
| Encomienda System | formal labor system established by the Spanish Crown in the Americas during the early 16th-century. Spanish monarch granted a specific number of Natives to Spanish colonists. |
| Transatlantic Slave Trade | Global commercial system that operated from the late 15th century to the 19th century involving the forced migration of millions of enslaved Africans across the Atlantic Ocean to the Americas |
| Columbian Exchange | massive, widespread transfer of plants, animals, foods, human populations, communicable diseases, and ideas between the Eastern and Western Hemispheres following Christopher Columbus's voyage to the Americans in 1492. |
| Asiento System | formal monopoly contract system operated by the Spanish Crown, crucial legal and financial mechanism that drove the transatlantic slave trade to Spanish colonies in the Americas. |
| Maize | 16th-century corn |
| Protestant Reform | 16th-century religious, political, and cultural upheaval that splintered Catholic Europe |