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Week 5

Generic Brand ClassIndication BBW Side Effects Counseling
Sofosbuvir Sovaldi Nucleotide analog NS5B polymerase inhibitor. Treatment of adult and pediatric patients with chronic HCV infection Risk of HBV reactivation in patients connected with HCV AND HBV. Test all patients for evidence of current or prior HBV infections before treatment. Fatigue, headache, nausea, insomnia. Bradycardia can occur when used with amiodarone. Must be used in combo with other antiviral medications. Not effective as monotherapy.
Atazanavir Reyataz HIV protease inhibitors HIV-1 infection in adults and pediatric in combo with other agents Hyperbilrubinemia (jaundice or yellowing) PR interval prolongation requires an acidic stomach environment, avoid or space doses significantly from PPI, antacids. Many DDI
Efavirenz Sustiva Non-nucleoside reverse transcriptase inhibitors (NNRTI) HIV-1 infection on combo with other antiretroviral agents dizziness, insomnia, impaired concentration, vivid dreams. serious depression, suicidal ideation/attempts Take on a empty stomach
Maraviroc Selzentry Antiretroviral, CCR5 Antagonist (Anti-HIV) CCR5-tropic HIV-1 infection in combo with other antiretroviral agents Hepatotoxicity Tropism requirement: before starting, screening test, must confirm the patient has CCR-5. Cough, fever, dizziness Dose must be adjusted based on concomitant medications
Elbasvir/grazoprevir Zepatier HCV Direct acting Antiviral (NS5A/NS3/4A) Treatment of chronic hep C virus genotypes 1 or 4 infection in adults and pediatric patients HBV reactivation in pt connected with HCV or HBV Hepatic ALT elevations: monitor ALT prior to drug treatment. Fatigue, headache and nausea. Report symptoms of liver injury, scubas fatigue, loss of appetite
Glecaprevir/Pibrentasvir Mavyert HCV Direct acting Antiviral (NS5A/NS3/4A) Treatment of chronic hep C virus genotypes 1,2,3,4,5 or 6 infection HBV reactivation in pt connected with HCV or HBV Headache fatigue, and nausea. CI: Pts with severe hepatic impairment (child Pugh C) Report signs of liver injury such as yellowing of the skin or eyes .
Nystatin systemic Bio-Statin Anti-fungal agent non-esphageal gastrointestinal candidiasis and oropharyngeal candidiasis Diarrhea, nausea, vomiting. Oral irritation and sensitization. Shake well before use. swish and swallow, retain the liquid in the mouth as long as possible before swallowing
Nystatin Topical Mycostatin Anti-fungal agent non-esphageal gastrointestinal candidiasis and oropharyngeal candidiasis irritation, dryness
Darbepoetin Aranesp Hematopoietic agent / ESA Anemia associated with CKD . Anemia for myelosuppressive chemotherapy. Increase risk of death, MI, Stroke, VTE. CKD: increase risk of serious cardiovascular events Cancer: risk of tumor progression HTN, cough, abdominal pain. Seizures and serious allergic reaction. SJS Do not sake the vial or syringe . monitor hemoglobin levels
Epoetin Alfa Epogen/ Procrit Hematopoietic agent / ESA Anemia associated with CKD . Anemia for myelosuppressive chemotherapy. Increase risk of death, MI, Stroke, VTE. CKD: increase risk of serious cardiovascular events Cancer: risk of tumor progression HTN, cough, abdominal pain. Seizures and serious allergic reaction. SJS Do not sake the vial or syringe . monitor hemoglobin levels
Entecavir Baraclude nucleoside reverse transcriptase inhibitor (NRTI) Hepatitis B Severe acute exacerbation pf hep B upon d/c. Risk of lactic acidosis and severe hepatomegaly. Headache, fatigue, dizziness, nausea. Montoir LFT Take on an empty stomach
Created by: angelicap
 

 



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