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Adenosine

cardiac pharmacology

QuestionAnswer
What is the classification is Adenosine ? Miscellaneous Nucleoside
What are the pharmacodynamics of Adenosine? -Binds to Adenosine A1 receptors that cause an efflux of potassium and inhibits calcium influx in slow potential cells -Causes hyperpolarization of autorhythmic cells (SA/AV nodes) -Slows AV conduction -Has a very short half-life
What are the indications of Adenosine? -Its the 1st lie med for stable narrow complex Supraventricular Tachycardia (SVT) - Regular and monomorphic wide complex tachycardia from a reentry Supraventricular Tachycardia SVT with Bundle Branch Block BBB
What two rhythms does Adenosine not convert ? Adenosine dose not convert A-fib or A-Flutter
What are the contraindications of Adenosine? - A Fib / A Flutter - Torsades de Pointes - Poison/drug induced tachycardia - 2nd or 3rd Atrioventricular Block (AVB ) - Wolff-Parkinson-White Syndrome (WPW)
What are the side effects of Adenosine? -Transient periods of -sinus bradycardia, -asystole, and -ventricular ectopy are common - Reduce initial dose in half in patients receiving dipyridamole or carbamazipine heart transplant, in patients, or if given by central venous access.
What is the dose for Adenosine? 1st Dose 6 mg rapid IV/IO push followed by a rapid flush of 20ml fluid 2nd Dose 12 mg rapid IV/IO push followed by a rapid flush of 20ml fluid
Created by: ejarami4
 

 



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