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NAPLEX
IV med principles
| Question | Answer |
|---|---|
| what is the common vein used for peripheral venous catheter? | cephalic vein in the arm |
| administering drugs into a smaller vein can cause what? | phlebitis, venous thrombosis, and interstitial fluid extravasation |
| central lines provide secure, long-term vascular access and are required for the administration of: | highly concentrated drugs (potassium chloride), long term abx, drugs that would cause severe phlebitis or tissue damage, drugs with a pH that is not close to blood pH, parenteral nutrition |
| where must the catheter tip be located to be considered a central line? | in a large vessel such as superior vena cava |
| vesicans are safer in what line method? | central line |
| examples of vesicants: | dopamine, NE, anthracyclines (doxorubicin), vinca alkaloids (vincristine), digoxin, foscarnet, mannitol, mitomycin, nafcillin, and promethazine |
| with promethazine what route should it be given? | it can cause severe tissue injury but IM is preferred |
| can you given promethazine intra-arterial or SC? | no it should not be used that way |
| what is an example of a container incompatibility? | DEHP can leach from the container into the solution and it is toxic and can harm the liver and possibly male fertility |
| what is the exception medication that can be put in a PVC container? | paclitaxel-albumin (abraxane) |
| drugs to mix in dextrose only | oxaliplatin, sulfamethoxazole, amphotericin B |
| what is an example of a dangeorus incompatibility | ceftriaxone and calcium, ceftriaxone cannot be mixed with any calcium-containing solutions due to the risk of precipitates |
| can lactated ringers be mixed with ceftriaxone | no it contains calcium and cannot be mixed |
| what are 2 mixes that together will be fatal | calcium & ceftriaxone and calcium & phosphate |
| what filter is used for parenteral nutrition to catch calcium-phosphate particulates and for injectable lipid emulsions | 1.2 micron |
| when is a filter needle or filter straw used | in compounding IV medications packaged in glass ampules |
| when does phenytoin require a filter? | requires a filter when adminsitered by continuous infusion, not IV push |
| for amphotericin B the lipid formulation what filter is required? | larger pore (5 micron) filter required |
| If furosemide and phenytoin crystallize if kept cold, what to do? | stored in room temperature |
| do not shake/agitate: | protein/blood products, alteplase, etanercept, rasburicase, insulin |
| do not use nitroprusside if it has turn blue: | blue indicates nearly complete dissociation to cyanide |
| what if dobutamine turns pink? | oxidation turns the solution slightly pink, but potency is not lost |
| what is the normal color of tigecycline? | yellow/orange |