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DM-Tranexamic Acid
| Question | Answer |
|---|---|
| Classification | Hemostatic agent Antifibrinolytic agent |
| Action | Prevents clot degradation by competing for TPA receptor sites |
| Indications | To assist with control of external bleeding |
| Contraindications | Allergy/Hyposensitivity |
| Cautions | None |
| Route | Topical |
| Onset, peak, duration | Onset: Immediate |
| Iatrogenic Overdose | The major adverse events due to tranexamic acid are the potential thromboembolic events, such as myocardial infarctions, deep vein thrombosis, and pulmonary embolism. |
| Iatrogenic Overdose continued(Intrathecal) | Severe pain, severe seizures, myoclonic twitching of facial muscles, ventricular fibrillation, coma, and death have been reported in patients following unintentional intrathecal administration of tranexamic acid |