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DM-Salbutomol

QuestionAnswer
Class Bronchodilator, Sympathomimetic
Action Relaxes the smooth muscle of the bronchial tree by stimulating beta-adrenergic receptors of the sympathetic nervous system.
Indications Bronchospasm
Contraindications Allergy/hypersensitivity
Cautions None
Side affects CNS: Restlessness, apprehension, tremor, dizziness, headache CVS: Arrhythmias, blood pressure changes, chest discomfort Respiratory: Coughing, bronchospasm GI: Nausea Skin: Pallor, flush, sweating
Dosage Nebulized: 5 mg MDI: 4x 100 mcg inhalations, may repeat up to 3 times
Pediatric Considerations and Dosing - Nebulized – Age < 1 years old: 2.5 mg – Age > 1 years old: 5 mg
Pediatric Considerations and Dosing - Metered Dose Inhaler – Not indicated in children under 10 kg – 10 – 20 kg: 5 x 100 mcg inhalations, may repeat up to 3 times – > 20 kg: 10 x 100 mcg inhalations, may repeat up to 3 times
Routes and Methods of Administration Nebulizer mask with oxygen at 6-8 liters per minute Metered dose inhaler (MDI) Ensure the MDI is shaken thoroughly and is allowed a full 30s between deliveries to allow the propellant to recharge
Onset, peak, duration Onset: 5-15 minutes (inhaled) Peak: 60-90 minutes (inhaled) Duration: 3-6 hours (inhaled)
Elimination Metabolized in liver into inactive metabolites
Iatrogenic Overdose Discontinue administration if signs of toxicity develop: heart rate > 150/minute (> 200/minute in pediatrics); severe tremors; ventricular arrhythmias.
Created by: Levelstorm3950
 

 



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