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DM-Naloxone

QuestionAnswer
Class Narcotic antagonist
Action Competes for opioid receptor sites. Displaces previously administered opioids from their receptors. No pharmacological activity on its own.
Indications Decreased level of responsiveness Respiratory depression - (Requiring BVM) Signs and symptoms: Suggestive of narcotic overdose (pinpoint pupils, drug paraphernalia, track marks, pill bottles etc.)
Contraindications Allergy, Neonate
Cautions Acute Withdrawal Symptoms/Aggression
Side Effects CNS - Excitation due to abrupt reversal of analgesia CVS – Tachycardia, hypertension, hypotension, arrhythmias Skin – Sweating
Dosage IN - Delivered Q 3 minutes in the following order until LOC and/or RR improve: 2.0mg, 2.0mg, and 2.0mg IM - Delivered Q 3 minutes in the following order until LOC and/or RR improve: 0.4mg, 0.4mg, 0.8mg and 2.0mg
Route IM, IN
Onset, Peak, Duration Onset: 3-5 minutes Peak: Unknown Duration: 45 minutes
Special Considerations Can cause abrupt state of narcotic withdrawal in the physically dependent patient Side effects such as agitation and aggressiveness can be symptoms of narcotic withdrawal
What can happen later to a patient after adminstering naloxone and their condition improves? In regards to the opioid drugs they have taken? Naloxone’s half-life is shorter than that of all opioids; therefore, a patient must be observed until the narcotic effect has worn off
Created by: Levelstorm3950
 

 



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