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20. Medicinal Plants
| Question | Answer |
|---|---|
| Cell Division Importance | Essential for growth, repair, and reproduction; billions of cell divisions occur constantly in living organisms. |
| Cell Division Errors (Cancer) | Cancer occurs when cell division becomes uncontrolled, leading to abnormal growth and potentially death. |
| Cell Growth | Includes cell enlargement and specialization, not just division. |
| Cell Division | Process where one cell divides into two identical daughter cells. |
| Cell Differentiation | Process in which cells become specialized for specific functions. |
| Meristems | Regions in plants where active cell division occurs. |
| Mitosis | Division of the nucleus that ensures each daughter cell receives identical genetic material. |
| Purpose of Mitosis | Maintains chromosome number and genetic stability in organisms. |
| Diploid Cells (2n) | Cells containing two sets of chromosomes (one from each parent). |
| Prophase | Chromosomes condense, nuclear membrane disappears, spindle fibers form. |
| Metaphase | Chromosomes align at the cell's equator and attach to spindle fibers. |
| Anaphase | Sister chromatids separate and move to opposite poles. |
| Telophase | Nuclear membranes reform and chromosomes unwind into chromatin. |
| Cytokinesis | Division of the cytoplasm that forms two separate daughter cells. |
| Cell Plate (Plants) | Structure that forms in plant cells during cytokinesis and becomes the new cell wall. |
| Phragmoplast | Structure made of vesicles and microtubules that helps form the cell plate. |
| Animal Cell Cytokinesis | Occurs by cleavage (cell membrane pinching inward). |
| Cell Cycle | Series of stages a cell goes through to grow and divide. |
| M Phase | Cell division phase (mitosis and cytokinesis). |
| Interphase | Growth and preparation phase before division. |
| G1 Phase | Cell grows, organelles increase, and proteins are produced. |
| S Phase | DNA is replicated, forming sister chromatids. |
| G2 Phase | Final growth and preparation for mitosis. |
| Interphase Importance | Cells spend about 90% of their time in interphase. |
| Chromosomes | Structures made of DNA and proteins that carry genetic information. |
| Genes | Units of heredity that code for proteins or RNA. |
| Chromatin | DNA and proteins in an uncondensed state. |
| Sister Chromatids | Identical copies of a chromosome joined at the centromere. |
| Centromere | Region where sister chromatids are attached. |
| Haploid (n) | Single set of chromosomes. |
| Diploid (2n) | Two sets of chromosomes. |
| Humans Chromosomes | 23 pairs (46 total chromosomes). |
| Homologous Chromosomes | Pairs of chromosomes with the same size and shape that carry genes for the same traits. |
| Madagascar Periwinkle | A plant used in cancer treatment; produces alkaloids used as chemotherapy drugs. |
| Vincristine and Vinblastine | Alkaloid drugs from Madagascar periwinkle that treat childhood leukemia by disrupting mitosis. |
| Mechanism of Madagascar Periwinkle Drugs | Interfere with microtubules and spindle formation, preventing cell division (mitosis). |
| Pacific Yew | A slow-growing conifer tree native to temperate forests of the Northwest United States. |
| Taxol (Paclitaxel) | A cancer-fighting compound derived from Pacific yew bark that treats ovarian and breast cancer. |
| How Taxol Works | Prevents microtubule breakdown, stopping cells from completing mitosis and halting cancer cell division. |
| Taxol Production Solution | Taxol can now be synthesized in laboratories, reducing the need for tree harvesting. |
| Plant-Based Medicines | Over 25% of modern medicines are derived from plants. |
| Deforestation Impact on Medicinal Plants | Over 70% of U.S. forests have been logged since the 1920s, threatening biodiversity and drug discovery. |
| Camptotheca acuminata (Happy Tree) | A tree from southern China containing camptothecin, used in colon and rectal cancer treatments. |
| Camptothecin | An alkaloid compound with anticancer properties. |
| Chinese Skullcap (Scutellaria baicalensis) | A traditional Chinese medicinal plant with compounds that may kill cancer cells while sparing healthy cells. |
| Mandrake | A plant historically used as an anesthetic; roots resemble human figures and were linked to the 'Doctrine of Signatures.' |
| Belladonna | A plant once used cosmetically to dilate pupils; now used in medicine to affect the nervous system and circulation. |