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| Question | Answer |
|---|---|
| What score gives an indirect measure of plaque burden in coronary arteries and is helpful in deciding if statins should be inititated in those with an intermediate to high 10-year ASCVD risk | CAC score (coronary artery calcium) |
| what is the threshold score for CAC in order to initiate a statin? | >100 agatston units |
| In what pt population do you NOT need to calculate an ASCVD risk score ? | for pts with clinical ASCVD, diabetes, or LDL >190 |
| what are natural products that can be effective at lowering LDL | red yeast rice, plant sterols, and fibrous foods |
| how does red yeast rice help at lowering LDL | contains naturally occurring HMG-CoA reductase inhibitors |
| Which natural product can help lower TG? | OTC fish oils but some products can increase LDL |
| what are the brand names for atorvastatin | Lipitor and Atorvaliq |
| what is Caduet | atorvastatin and amlodipine |
| what is the max daily dose of lovastatin if pt is also taking amlodipine? | 20mg |
| what is the max daily dose of simvastatin if pt is also taking amlodipine? | 20mg |
| Besides gemfibrozil what other medication can increase the risk of myopathy? | niacin |
| which statin does NOT require renal dose adjustments | atorvastatin |
| what is the max daily dose of rosuvastatin when taking cyclosporine? | 5mg |
| what is the max daily dose of atorvastatin when taking cobicistat? | 20mg |
| rhabdomyolysis can lead to what | acute renal failure |
| what is one OTC med that can provide benefit for mild muscle symptoms | coenzyme q10 |
| what to do if myalgia occurs? | hold statin, check CPK, and after 2-4 weeks: rechallenge with the same statin at same or lower dose |
| when should the non-statin therapy be considered | if the pt is unable to tolerate a statin after at least 2 attempts |