click below
click below
Normal Size Small Size show me how
Anticoagulation B/G
Anticoagulation - Brands / generics
| Question | Answer |
|---|---|
| Lovenox | Enoxaparin |
| Coumadin | warfarin |
| Jantoven | warfarin |
| Advil | ibuprofen |
| Doan's | magnesium salicylate |
| Pradaxa | dabigatran |
| Xarelto | rivaroxaban |
| Savaysa | edoxaban |
| Praxbind | idarucizumab |
| Eliquis | apixaban |
| Angiomax | bivalirudin, IV |
| Arixtra | - Fondaparinux - A direct factor Xa inhibitor - CI if CrCl < 30 mL/min - SQ PPx DVT, treat DVT/PE |
| Fragmin | - Dalteparin - LMWH (HIT) - SQ - Room tem |
| Innohep | - Tinzaparin - LMWH (HIT) |
| Iprivask | - Desirudin (d/c) |
| Pletal | - Cilostazol, antiplatelet |
| Aggrastat | - Tirofiban - Glycoprotein (GP) Ilb/Illa inhibitor - IV - ACS indication |
| Plavix | - Clopidogrel 75 & 300 mg strength - CYP2C19: NO Esomeprazole / Nexium, omeprazole / Prilosec - Irreversible P2Y12 - LD / STEMI w fibrinolytic 300mg (NO LD > 75 yrs) - LD / PCI: 600mg - NO renal dose adj |
| Effient | - Prasugrel - Irreversible P2Y12 inhibitor, thienopyridine - ADP blocker - LD: 60mg POQD, MD: 10mg QD regardLESS of food |
| Brilinta | - Ticagrelor -Reversible P2Y12 - ASA dose max 100 mg - ADP blocker - LD: 180 mg POQD; MD: 90 BID, then 60 BID if after 1 yr (check) - CYP3A4 substrate |
| Zontivity | - Vorapaxar - Protease-activated receptor-1 (PAR-1) antagonist - Indication: MI, PAD - CI: strock, TIA, ICH |
| Persantine | - Dipyridamole - Antiplatelet - Vasodilator - HyPOtension - Monitor BP / HR |
| Activase | - Alteplase - CI: ICH, BP > 185/110 mmHg, h/x hemorrhagic stroke (ok for menstruation) - Reconstitute no more than 8 hrs before use (no preservative) - NOT shake |
| Lovenox strengths - 3 - 4 - 6 - 8 - 1. - 1.2/0.8 - 1.5/1 | - 30mg / 0.3mL - 40... - 60... - 80 mg / 0.8mL - 100mg / 1mL - 120mg / 0.8mL - 150mg / 1 mL |