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DM-Ibuprofen

QuestionAnswer
Classification Analgesic, antipyretic, NSAID
Action Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic and antipyretic activities by inhibiting prostaglandin synthesis.
Indications Mild-moderate pain
Contraindications (KABAP)Kidney problems(dysfunction) Allergy/Hypersensitivity, Bleeding, Anticoagulants, Pregnancy
Cautions (COD)Cardiac emergency(myocardial infarction), Other NSAID use, Dehydration Cardiac,
Side Effects Gastrointestinal upset, ranging from abdominal discomfort to gastric ulceration, bleeding, and perforation.
Dosage 300-400 mg PO; may repeat every 4-6 hours; maximum daily dose 1,200 mg/day
Pediatric Considerations and Dosing Follow weight-based dosing 10 mg/kg PO; may repeat once after 6 hours; maximum daily dose 40 mg/kg/day
Route PO, by mouth
Onset, Peak, Duration Onset: 30-60 minutes Peak: 1-2 hours Duration: 4-6 hours
Elimination Metabolized by the liver, Majority is excreted by the renal system
What is the iatrogenic overdose for ibuprofen? The most common symptoms of NSAID overdose are gastrointestinal irritation and CNS depression. Care is primarily supportive.
Created by: Levelstorm3950
 

 



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