Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
CC - PRELIM
L2
| Question | Answer |
|---|---|
| Involves all three phases of testing | QA |
| Overall program that ensures that the final results reported by the laboratory are correct | QA |
| It is concerned with a l factors that affect the test results from pre-analytic, analytic, and post-analytic phases | QA |
| Part of quality assurance | QC |
| Process of ensuring that analytical results are correct - System of ensuring accuracy and precision in the laboratory | QC |
| Done before actual testing, usually during the night shift in laboratories | QC |
| KINDS OF QUALITY CONTROL | 1. INTRAlab 2. INTERlab |
| KINDS OF QUALITY CONTROL ; o Done everyday o Internal quality control o Important in daily monitoring | Intralab Quality Contro |
| KINDS OF QUALITY CONTROL ; o Analyses of control samples together with patient specimens | Intralab Quality Contro |
| KINDS OF QUALITY CONTROL ; o External quality control o Maintains long-term accuracy of methods | Interlab Quality Control |
| Involves proficiency testing programs that periodically provide samples of unknown concentrations of analytes to participating laboratories (ex: NEQAS) | Interlab Quality Control |
| (NEQAS) | National External Quality Assessment Scheme |
| Proficiency program that sends samples laboratories | National External Quality Assessment Scheme |
| TYPES OF REAGENTS | 1. Blank 2. Standard 3. Control |
| TYPES OF REAGENT ; ○ Reagent without sample ○ Reagent without analyte added | blank |
| TYPES OF REAGENT ; substances that can be tested for | analyte |
| TYPES OF REAGENT; ○ Reagents with only one analyte ○ Most specific analytical solution | standard |
| TYPES OF REAGENT; ○ Its value will tell the concentration of the unknown ○ Only run when a specific standard is not running correctly | standard |
| TYPES OF REAGENT; ○ Run everyday ○ Reagent with many analytes ○ Resembles patient sample | Control |
| Control type of reagent has 3 types ... | 1. Commercially Prepared 2. Non-commercially prepared 3. Pooled px sample |
| Commercially prepared ex: | Manufactured by a company |
| Non-commercially prepared ex: | 1) Leftover sera (hemolyzed) 2) Animal blood (cow blood) 3) Expired blood bank plasma 4) Fasting human donor |
| Pooled px sample | Different specimens mixed together |
| REAGENT BOX Includes the following: | a) Specific standard b) Package insert c) Actual reagent d) Standard reagent |
| QC PARAMETERS | 1. Validity 2. Reliability 3. Sensitivity 4. Specificity |
| QC PARAMETER; ○ Accuracy of the test ○ How close the result is to its true value | Validity |
| QC PARAMETER; ○ Refers to how well the test measures what it is supposed to measure ○ Theability to distinguish which individuals have the disease and which do not | Validity |
| QC PARAMETER; ○ AKA: Repeatability, Reproducibility ○ Precision of the test | Reliability |
| QC PARAMETER; ○ How close the values are to one another ○ Refers to how wel the test performs in use over time | Reliability |
| QC PARAMETER; The ability of the test to detect the smallest amount of analyte | Sensitivity |
| refers to the ability of the test to identify correctly those who have the disease from al individuals with the disease | Diagnostic Sensitivity |
| Diagnostic Sensitivity FORMULA | - |
| QC PARAMETER; THE ability of the test to detect substances without interference | Specificity |
| Specificity FORMULA | - |
| refers to the ability of the test to identify correctly those who do not have the disease from al individuals free from the disease | Diagnostic Specificity |
| leads to needed care & treatment | TP |
| ideal result/situation | TN |
| causes unnecessary treatment | FP |
| causes false sense of security | FN |
| TYPES OFERRORS | 1. Systematic 2. Random |
| - Predictable errors | Systematic |
| An error that is constant when measurements are made under the same conditions | Systematic |
| Systematic Error causes? | Deterioration of reagents Improperly made standard solutions Contaminated solutions Calibration problems Failing instrumentations |
| Unpredictable Errors | Random Error |
| Often due to instrument, operator, and environmental conditions | Random Error |
| Random Error causes? | Pipetting error Mislabelling of samples Temperature fluctuation Improper mixing of sample and reagent |
| Quality control chart Most commonly used histogram in quality control | LEVEY-JENNINGS CHART |
| sheets of rectangular coordinate graphing paper where data for sequential analysis are plotted to locate the source of error | Histogram |
| The results of the control fall WITHIN confidence limit | In CONTROL |
| The values of the control fall OUTSIDE the confidence limit | OUT of CONTROL |
| Gradual change - Formed by the control that continue to either increase or decrease for a period of SIX or more consecutive days | TREND |
| Abrupt change in ONE SIDE of the mean With no tendency toward either a consistent fall or rise Formed by the control that distribute themselves on ONE SIDE (above or below) the mean | SHIFT |
| Caused by WILD errors Values which are far from the main set of values | OUTLIERS |
| WESGUARD MULTIRULE SYSTEM is developed by? | Dr. James O. Westgard |
| Based on statistical concepts which is a combination of decision criteria or rules to assess if a system is in control | WESGUARD MULTIRULE SYSTEM |
Created by:
twisa_heart