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BMB 4450
Vitamins and Minerals
| Question | Answer |
|---|---|
| What is the function and storage location of fat-soluble vitamins? | non-coenzyme function; liver and adipose tissue |
| What is the function and storage location of water-soluble vitamins? | coenzyme/cofactor function; circulated in water-filled sites |
| What is the GULU gene? | the gene responsible for synthesizing vitamin C |
| Fat-soluble vitamins are all derived from what precursors? | isoprene/terpene-based precursors |
| Vitamin A, vitamin D, vitamin E, and vitamin K are examples of what type of vitamins? | fat-soluble |
| Vitamin A is derived from what molecule? | beta-carotene |
| What is rhodopsin? | a molecule consisted of vitamin A and opsin protein for light-absorbing functions |
| What are photopsins? | light-absorbing molecules contain retinal but not rhodopsins |
| The main forms of vitamin D are? | D2 and D3 |
| What is the active vitamin D metabolite? | calcitriol |
| What is vitamin D receptor (VDR)? | a transcription factor that interacts with calcitriol to modulate gene expression of Ca-transport proteins |
| Rickets is a condition that causes softening and weakening of bones. What vitamin deficiency is this caused by? | vitamin D |
| What is the function of vitamin E (tocopherols)? | anti-oxidant functions |
| Vitamin C, Vitamin B1, B2, B3, B5, B6, B7, and B12 are examples of what type of vitamins? | water-soluble |
| Vitamin C acts as an anti-oxidant and required for the formation of what type of molecule? | collagen |
| What is scurvy and a deficiency in what vitamin causes it? | a disorder characterized by decreases cross-linking of propeptides in collagen caused by a vitamin C deficiency |
| What is the function of vitamin B1 (thiamine)? | coenzyme for many dehydrogenase complexes |
| What is the function of vitamin B2 (riboflavin)? | precursor for FAD and FMN |
| What is the function of vitamin B6 (pyridoxine)? | converted into PLP (pyridoxial-5-phosphate) |
| What is the function of vitamin B12 (cobalamin)? | a larger structure mainly found in the mitochodria and used for RBC formation |
| What is the function of vitamin B3 (niacin)? | precursor of NAD+ and NADP+ |
| What is the function of vitamin B5 (pantothenic acid)? | precursor to coenzyme A and acyl carrier protein (ACP) |
| What is the function of vitamin B7 (biotin)? | coenzyme for carbon dioxide fixation reactions |
| Symptoms of the disorder beriberi include complications with the TCA cycle and PPP pathway. Beriberi is caused by a deficiency in what vitamin? | thiamine (B1) |
| What is the function of the protein transferrin? | transport iron throughout the body |
| What is the function of the protein ferritin? | store iron in tissues and cells |
| Copper is a mineral that plays important roles in what two complexes? | cytochrome C oxidase and superoxide dismutase |
| What two minerals are used as components of the superoxide dismutase enzyme? | copper and zinc |