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Chapter 10
| Question | Answer |
|---|---|
| Substances that are naturally produced by certain microorganisms that can inhibit or destroy other microorganisms are called _________. | antibiotics |
| Antimicrobials that are effective against a wide variety of microbial types are termed _________. | broad-spectrum drugs |
| Antibiotics are derived from all of the following except _________. | Staphylococcus |
| Important characteristics of antimicrobial drugs include _________. | Low toxicity for human tissue, high toxicity against microbial cells, do not cause serious side effects in humans, stable and soluble in body tissue and fluids |
| The use of a drug to prevent a person at risk of an imminent infection is called _________. | prophylaxis |
| The use of any chemical in the treatment, relief, or prophylaxis of a disease is called _________. | chemotherapy |
| Selective toxicity refers to _________. | damage to the target organisms but not host cells |
| Each of the following affect cell walls except _________. | erythromycin |
| Aminoglycosides _________. | attach to the 30S ribosomal subunit and disrupt protein synthesis |
| Each of the following target bacterial ribosomes except _________. | polymyxins |
| Sulfonamides _________. | block folic acid synthesis |
| Sulfa drugs work on _________. | folic acid biosynthesis |
| A chemical that inhibits beta-lactamase enzymes is _________. | clavulanic acid |
| What type of chemical will allow some bacteria to be resistant to many penicillins? | Penicillinase |
| Which antimicrobial does not inhibit cell wall synthesis? | Tetracycline |
| Which drug is used to treat cases of tuberculosis? | Isoniazid |
| What cell wall inhibiting drug is used in cases of penicillin and methicillin resistance? | Vancomycin |
| Clavulanic acid _________. | inhibits B-lactamase activity |
| Gram-negative rods are often treated with _________. | aminoglycosides |
| Which antimicrobial does not interfere with protein synthesis? | Trimethroprim |