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clinchem final2
| Question | Answer |
|---|---|
| potassium ISE | valinomycin |
| sodium ISE | silicate in glass |
| CO2 ISE | severinghaus |
| oxygen ISE | clarke |
| total protein reference interval | 6.5-8.3 g/dL |
| Albumin reference interval | 3.5-5.1 g/dL |
| globulin reference interval | 2-3 g/dL |
| α2 macroglobulin | increased in nephrosis |
| haptoglobin | binds free hemoglobin |
| ceruloplasmin | transports copper |
| IgG | antibody capable of crossing the placenta |
| BNP | neurohormone, marker for CHF |
| what is the reference method for proteins? | kjeldahl |
| alpha1 antitrypsin | APR, marker for emphysema |
| transferrin | transports iron |
| CEA | marker for colon cancer |
| CA 125 | marker for ovarian cancer |
| alkaptonuria | enzyme deficiency in tyrosine pathway leading to homogentisic acid accumulating in blood & appearing in urine |
| CSF glucose reference interval | 50-80 mg/dL |
| fasting glucose reference interval | <100 mg/dL |
| criteria for diabetes diagnosis | A1c > 6.5% fasting glucose of >126 mg/dL 2 hour postload + random glucose of >200 mg/dL |
| von gierke disease | glycogenolysis can't occur --> glycogen buildup in the liver |
| total cholesterol reference interval | 140 - 200 mg/dL |
| HDL reference interval | 40-75 mg/dL |
| LDL reference interval | 50-130 mg/dL |
| triglycerides | 60-150 mg/dL |
| Apo A | associated with HDL; inversely related to CAD risk |
| Apo B | found on all lipoproteins except ApoA |
| Lp (a) | structurally similar to plasminogen |
| trinder reaction | uses peroxidase to oxidize H2O2 |
| urea reference intervals for plasma and urine | plasma: 6-20 mg/dL urine: 12-20 mg/dL |
| uric acid reference intervals for men and women | men: 3m5-7.2 mg/dL women: 2.6-6.0 mg/dL |
| creatinine reference intervals (men and women) | men: 0.9-1.2 mg/dL women: 0.6- 1.1 mg/dL |
| ammonia reference intervals in adults and kids | adults : 19-60 mg/dL kids: 68-136 mg/dL |
| reference ranges: total bilirubin unconjugated conjugated | total : 0.2-1 mg/dL conjugated: 0.0-0.2 mg/dL unconjugated: 0.2-0.8 mg/dL |
| gilberts syndrome | defective bilirubin transport into hepatocytes |
| crigler najjar syndrome | UDPG deficiency --> increased unconjugated bilirubin |
| dubin johnson + rotor syndrome | defective secretion of unconjugated bilirubin |
Created by:
kingsleya27