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exam 1 patho

immune

QuestionAnswer
Type 1 (IgE / Mast cell) IgE triggers mast cells → histamine release     •    Causes itching, swelling, airway constriction allergic reaction
type || (antibody-mediated) Antibodies attack your own cells     •    Leads to cell destruction body attacks cells directly
Type ||| (immune complex ) Antigen + antibody form complexes that deposit in tissues     •    Causes inflammation and damage     •    Example:     •    Glomerulonephritis (chatgpt://generic-entity?number=4)     •    Keyword: “complexes get stuck
Type IV (delayed T-cell) Delayed (24–72 hours)     •    No antibodies — T-cells only     •    Examples:     •    Tuberculin skin test     •    Contact dermatitis     •    Transplant rejection     •    Keyword: delayed response
Direct extension infection spreads to nearby tissue
Seeding spreads through blood to distant sites
Prodrome early vague symptoms (fatigue, malaise)
Septicemia bacteria in blood
Vasoconstriction narrowing of blood vessels
Gram negative bacteria with outer membrane (harder to treat, releases toxins)
Septic shock severe infection → low BP + organ failure
Hypersensitivity exaggerated immune response
Insecticide chemical used to kill insects (toxic exposure risk)
Formaldehyde chemical carcinogen (preservative, irritant)
Splenomegaly enlarged spleen
Hepatomagely enlarged liver
Contact dermatitis skin reaction (Type IV)
Transplant rejection immune attack on transplanted organ
Hemolytic disease destruction of red blood cells
Pruritus itching
Glomerulonephritis kidney inflammation
H. Pylori causes ulcers
Cellular stress anything that disrupts balance (low oxygen, toxins, infection)
Atrophy shrink
Hypertrophy grow bigger
Chain of infection Infectious agent     2.    Reservoir     3.    Portal of exit     4.    Transmission     5.    Portal of entry     6.    Host
Sodium (NA) Water balance     •    Low = confusion     •    High = dehydration
Potassium (K) HEART ❤️     •    Low = arrhythmias     •    High = cardiac arrest
Calcium (CA) Bones + muscles     •    Low = spasms     •    High = weakness
Magnesium (MG) Neuromuscular control (water)
Isotonic normal
Hypotonic cells swell
Hypertonic cells shrink
Diffusion high → low
Osmosis water moves
Active transport uses ATP
Created by: ls99510
 

 



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