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RxPrep

Endocarditis and CAP

QuestionAnswer
Drug used to break biofilms in prostethic heart valves? Rifampin
Which drug providers synergy and is recommended for difficult endocarditis infections, especially in heart valves? Gentamicin
Peaks and troughs for gentamicin? Peaks 3-4 Trough: < 1
Preferred regimen for endocarditis with viridians group strep? Penicillin or ceftriaxone +/- gentamicin Alt: use vanc in pen allergies
Preferred regimen for endocarditis with MSSA? (Nafcillin or cefazolin) + gentamicin *add rifampin for prostethic valve
What antibiotic should we add if they have a prosthetic valve for endo and have staph infection? Rifampin
Preferred regimen for endocarditis with MRSA? Vanc *add gent and rifampin for prosthetic valve
Preferred regimen for endocarditis with enterococci (assume no VRE)? (penicillin or ampicillin) + gentamicin alt: amp + high dose Rocephin
Preferred regimen for endocarditis with enterococci when we cant rule out VRE? Dapto or linezolid
Created by: cdaughtry
 

 



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