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RxPrep
Septic Shock/Pressors/HAP/VAP
| Question | Answer |
|---|---|
| Which pressor is first line? | Norepinephrine |
| Which pressors can cause hyperglycemia? | Mainly epi, also dopamine at higher doses |
| When does the book say to use double coverage for PSA? | IV abx in last 90 days, local resistance > 10%, in hopstial > 5 days prior to VAP |
| Which 3rd gen ceph covers PSA? | Ceftazidime |
| When does the book say to cover MRSA in HAP/VAP? | IV abx in last 90 days, MRSA prevalance > 20%, prior MRSA infection, (+) MRSA nare |
| Which FQs can be used for respiratory infections? | Moxi and Levo (NOT Cipro) |
| When is monotherapy with FQs appropriate in CAP? | Non-severe admission, DO NOT USE monotherapy FQs in severe inpatient CAP |
| What is the dosing for dopamine? | 3 different dosings Low: 1-4mcg/kg/min Medium: 5-10 High: 10-20mcg/kg/min |
| Which pressors cause extravasation | All of them |
| Drug use to treat extravasation? | Phentolamine |
| Max duration of NTG? | Tachyphylaxis after 48 hours |
| Side effects of NTG? | Tachycardia, headache, Avoid when SBP < 90 |
| Warnings of NTG? | Severe hypotension, Increased intracranial pressure. |
| Which nitrate can cause cyanide toxicity? | nitroprusside (thiocyanate toxicity), worse in renal/hepatic impairment |
| What are the inotrope drugs used in critical care? | Dobutamine (beta-1 agonist) and milrinone (PDE-3 inhibitor) |
| What is MAP goal on pressors? | MAP >/= 65 |
| 1st line for hypovolemic shock? | Fluids (mainly crystalloids like LR) |
| Sepsis/Septic shock is what type of shock? | Distributive shock |
| How do NE and EPI work differently? | Epi: a1, b1, and b2 NE: mainly a1, > b1 (no beta-2) |