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GI 1
BDK
| Generic Name | Brand Name | Pharmacologic Category | Common Indication | Key Side Effects | Other Notes | US Boxed Warnings | Classification |
|---|---|---|---|---|---|---|---|
| Dicyclomine | Bentyl | Anticholinergic; Antispasmodic | IBS | Blurred vision, Dizziness, Xerostomia, Drowsiness, Constipation | CI in GI obstruction, reflux esophagitis, acute hemorrhage w/ cardiac instability, obstructive uropathy, glaucoma | N/A | N/A |
| Linaclotide | Linzess | Guanylate cyclase C agonist | IBS-C, opioid-induced constipation | Abdominal pain, Diarrhea | Mechanical GI obstruction | Don't use in patients < 2 years old (risk of death due to dehydration) | N/A |
| Polyethylene glycol 3350 | MiraLax | Osmotic laxative | Constipation | Electrolyte imbalance, Abdominal cramping | CI w/ bowel obstruction | N/A | OTC |
| Lactulose | Enulose, Constulose | Osmotic laxative | Constipation, hepatic encephalopathy | Abdominal distention, Flatulence, Diarrhea, Abdominal cramps | N/A | N/A | N/A |
| Senna | Ex-Lax, Senokot | Stimulant laxative | Constipation | Electrolyte imbalance, Abdominal cramping | N/A | N/A | OTC |
| Docusate | Colace | Stool softener | Prevent straining during defacation | N/A | Don't use w/ mineral oil | N/A | OTC |
| Dexamethasone | DexPak, DoubleDex | Corticosteroid | Inflammatory diseases, cerebral edema, CINV | Hyperglycemia, Increased appetite w/ weight gain, Depression, Irritability, Anxiety, Restlessness, Insomnia, Osteoporosis (chronic use), Cushing's syndrome (chronic use) | Risk of adrenal suppression w/ prolonged use | N/A | N/A |
| Methylprednisolone | Medrol, Solu-Medrol | Corticosteroid | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | Hyperglycemia, Increased appetite w/ weight gain, Depression, Irritability, Anxiety, Restlessness, Insomnia, Osteoporosis (chronic use), Cushing's syndrome (chronic use) | Risk of adrenal suppression w/ prolonged use | N/A | N/A |
| Prednisolone | Orapred | Corticosteroid | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | Hyperglycemia, Increased appetite w/ weight gain, Depression, Irritability, Anxiety, Restlessness, Insomnia, Osteoporosis (chronic use), Cushing's syndrome (chronic use) | Risk of adrenal suppression w/ prolonged use | N/A | N/A |
| Prednsione | Deltasone, Rayos | Corticosteroid | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | Hyperglycemia, Increased appetite w/ weight gain, Depression, Irritability, Anxiety, Restlessness, Insomnia, Osteoporosis (chronic use), Cushing's syndrome (chronic use) | Risk of adrenal suppression w/ prolonged use | N/A | N/A |
| Hydrocortisone | Topical: Cortaid IV: Solu-Cortef | Corticosteroid | Topical: Inflammation, rash PO/IV: Acute illness, adrenal insufficiency | Hyperglycemia, Increased appetite w/ weight gain, Depression, Irritability, Anxiety, Restlessness, Insomnia, Osteoporosis (chronic use), Cushing's syndrome (chronic use) | Risk of adrenal suppression w/ prolonged use | N/A | Topical: OTC |