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RxPrep

Pregnancy and Vaccines (CH 48 and 20)

QuestionAnswer
Warfarin in pregnancy? No
Statins in pregnancy? No
Valproic acid in pregnancy? No
Topiramate in pregnancy? No
FQs in pregnancy? Avoid
Tetracyclines in pregnancy? Avoid
First-line HTN drugs in pregnancy? Labetalol, nifedipine ER, methyldopa
Aliskirin in pregnancy? No
Preferred diabetes treatment in pregnancy? Insulin
Oral options sometimes used for DM in pregnancy? Metformin and glyburide
Can aspirin be used in pregnancy? Almost always no, can ONLY be used in low doses for preeclampsia prevention in pregnant T1/T2 diabetes patients.
Preferred ICS in pregnancy? Budesonide
Rescue inhaler pregnancy? Albuterol alone or ICS-formoterol combos are preferred for rescue
LABA use in pregnancy? Can continue with ICS
All ICS safe in pregnancy? Yes
Hypothyroidism treatment pregnancy? Levothyroxine, but must increase dose by 30-50%
HYPERthyroid drug(s) 1st trimester? PTU or methimazole
Preferred anticoagulant pregnancy? LMWH preferred, CAN use heparin though
Mechanical valve pregnancy? LMWH preferred, CAN use heparin though, NEVER warfarin
Safe antibiotics in pregnancy? Penicillins, cephalosporins, and most macrolides (NOT clarithromycin)
Which ABX should NOT be used in pregnancy? Avoid FQs and tetracyclines
Preferred agents for UTI in pregnancy? 1) Cephalexin 2) Amoxicillin
Alternative agents in UTI in pregnancy? **Macrobid, **Bactrim, and fosfomycin **Avoid these late pregnancy
Vaginal fungal infection in pregnancy? Topical antifungal, avoid systemic azoles
First-line nausea pregnancy? Pyridoxine +/- doxylamine
First-line GERD therapy in pregnancy? Lifestyle first, then calcium carbonate
Next step GERD therapy in pregnancy? After lifestyle and Tums fail, can use H2 blocker or PPI
First line constipation tx for pregnancy? Fiber
Can pregnant patients take stool softeners? Docusate is ok
Can pregnant patients use Miralax? Yes
First-line allergy pregnancy? Cromolyn
Ideal Antihistamines in pregnancy? Chlorpheniramie Loratidine, Cetirazine
Preferred nasal steroid pregnancy? Budesonide
Oral decongestants in pregnancy? NOT in first trimester
NSAIDs in pregnancy? Avoid, esp after >20 weeks
Preeclampsia prevention drug? Low-dose aspirin, BUT only after 1st trimester and in high risk patients
Tdap in pregnancy timing? Third trimester of each pregnancy
Tdap purpose in pregnancy? Prevent pertussis in infant
RSV vaccine pregnancy timing? 32–36 weeks gestation
Flu vaccine age minimum 6 months or older
Flu vaccine in pregnancy? Yes, just no live flu shots
HPV vaccine brand? Gardasil 9
HPV age range? 9–26 years
Dosing for HPV vaccine? HPV dosing <15 years? 2 doses HPV dosing ≥15 years? 3 doses
CI of HPV vaccine? Severe yeast allergy
MMR brands? M-M-R II, Priorix
RSV pregnancy vaccine? Abrysvo
RSV infant monoclonal? Nirsevimab (Beyfortus)
RSV antibody for infants? Palivizumab (Synagis)
PCV20 brand? Prevnar 20
PCV15 brand? Vaxneuvance
PCV21 brand? Capvaxive
Adult pneumococcal option 1? PCV20 alone
Adult pneumococcal option 2? PCV15 then PPSV23
PCV15 to PPSV23 interval? 12 months
MenABCWY brand? Penbraya
MenB brands? Bexsero, Trumenba
MenACWY brands? Menactra, Menveo, MenQuadfi
MenACWY schedule adolescents? 11–12 yrs and 16 yrs
MenB optional age? 16-23 years old
Hep A brands? Havrix, Vaqta
Hep B brands? Engerix-B, Heplisav-B, Recombivax HB
When is Hep B given for infants? Within 24 hours of birth
Created by: cdaughtry
 

 



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