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Bone Diseases
| Term | Definition |
|---|---|
| Multiple Myeloma | Malignant proliferation of plasma cells. |
| Fibrosarcoma | Solitary collagenous tumor seen most often in the diaphysis (metaphysis) of the femur or tibia... progression from inside out. |
| Osteomyelitis | Type of infection in which bacteria secretes toxins that promote bone necrosis. |
| Osteoporosis | Metabolic disease in which the density of bone is reduced but the remaining bone has a normal proportion of minerals to organic content. |
| Osteomyelitis | Symptoms include fevers, inflamed lymph nodes, local pain and swelling... progressing to nausea, muscle spasms, and possibly lesions of the bone |
| Osteosarcoma | Most common osteogenic tumor, frequently found in adolescents and young adults, tumor found in the bone marrow of humerus, femur, or tibia. |
| Rickets | Vitamin D deficiency where epiphyseal cartilage grows at plate but fails to ossify/calcify, the growing bones become deformed and bend under weight bearing. |
| Chondrosarcoma | Affects femur and pelvis, tumor is composed of large masses of hyaline cartilage and fibrous tissue, erodes the bone, enlarges it, and often invades the joint cavity, therefore amputation is often the treatment of choice |
| Osteochondrosis | Family of avascular bone diseases occurring in children, skeletal deformities result from disturbances in the blood supply to the ossification centers of growing bones. |
| Osteomalacia | Metabolic bone diseases characterized by inadequate mineralization of bone. |
| Osteitis Deformans (Paget's disease) | Rapid and disorganized bone remodeling activity, bones are poorly constructed and weakened. Characterized by proliferation of osteoclasts and compensatory increased osteoblastic activity. |
| Achondroplasia | inherited disease involving a disruption in the conversion of cartilage to bone during development. |
| Gout | Type of acute arthritis caused by the accumulation of uric acid crystals in the synovial fluid of joints, usually in lower limbs causing pain and swelling |
| Rheumatoid Arthritis | Degeneration of hyaline cartilage |