Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
NAPLEX
ACS- seminar
| Question | Answer |
|---|---|
| what are the most sensitive and specific biomarkers for ACS? | troponin I and T |
| what do the antianginals do in ACS? | decrease myocardial oxygen demand or increase blood flow to relieve ischemia |
| what medications should be avoided in the acute setting | NSAIDs (except aspirin), IR nifedipine |
| Is morphine give to all the patients | No, reserved for those with unacceptable chest discomfort despite other treatments |
| When do you NOT use IV NTG? | when SBP <90, HR <50 or with a right ventricular infarction |
| What type of aspirin coating should be administered to the patients? | Non-enteric coating, chewable aspirin |
| what is the loading dose of clopidogrel for PCI | 600mg |
| what is the loading dose of plavix? | 300-600mg |
| what is the maintenance dose of plavix? | 75mg PO daily |
| when is prasugrel indicated? | ACS managed with PCI |
| what are the CI to using Effient? | active serious bleeding, history of stroke or TIA |
| Which P2Y12 in not recommended for pt >75 YO due to high bleeding risk? | Prasugrel |
| What is the maintenance dose of prasugrel if the pt weights <60kg? | 5mg daily |
| Which P2Y12 gets affected by >100mg of aspirin? | Ticagrelor - reduces effects |
| what are the side effects to Ticagrelor? | bleeding, dyspnea, increased SCr and UA |
| How long do the effects last of Cangrelor after drug discontinuation? | 1 hour |
| which what P2Y12 should you avoid simvastatin and lovastatin doses of greater than 40mg/day? | Ticagrelor |
| which drugs increase bleeding risk? | Antiplatelets, anticoagulatns, SSRI/SNRIs, warfarin, NSAIDs |
| what are the CI to fibrinolytics? | Active internal bleeding, history of recent stroke, server uncontrolled HTN, recent trauma, prior intracranial hemorrhage |
| what are the 3 medications used for secondary prevention for ACS that will be needed indefinitely without requirements | aspirin, statin, nitroglycerin |
| what medications in ACS have a CI to history of stroke? | Prasugrel and fibrinolytics |
| Prasugrel | Effient |
| MOA of nitrates in ACS: | antianginal: dilate coronary arteries and improve collateral blood flow: decrease preload and afterload; reduces chest pain |
| when do you start a BB on a patient with ACS | within the first 24 hours |
| which P2Y12 has a CI or history of stroke or TIA | prasugrel |
| which P2Y12 do not not initiate if CABG likely? | prasugrel |
| which P2Y12 do you avoid the use if CABG likely? | ticagrelor |
| which P2Y12 has a side effect of dyspnea? | ticagrelor |
| When using ticagrelor and aspirin, what is the aspirin maintenace dose that you shouldn't exceed? | 100mg |
| when using cangrelor (Kengreal) do you stay with the injection forever? | no, transition to an oral P2Y12 inhibitor after PCI |
| how long are the drug effects lasting when discontinuing cangrelor? | 1 hour |
| with what medication do you avoid clopidogrel with due to increasing its effects and causing hypoglycemia? | repaglinide |
| what is the warning with using vorapaxar? | do not use in severe liver impairment |
| what are the CI to using fibrinolytics | active internal bleeding, history of recent stroke, and severe uncontrolled hypertension |
| what should be prescribed to a pt who has a history of GI bleed and taking triple antithrombotic therapy? | PPI |
| what are the contraindications to a spironolactone | SCR >2.5 (M) and Scr >2 in F or hyperkalemia >5 |
Created by:
KaHerre12