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Chapter 6 powerpoint
| Term | Definition |
|---|---|
| Skeletal cartilage | Highly resilient cartilage tissue that consists primarily of water, contains no blood vessels or nerves, and is made of chondrocytes in lacunae within a jelly-like matrix. |
| Perichondrium | Layer of dense connective tissue surrounding cartilage; helps resist outward expansion and contains blood vessels for nutrient delivery. |
| Types of cartilage | Three types: hyaline (support, flexibility, resilience), elastic (elastic fibers; ear and epiglottis), fibrocartilage (thick collagen; great tensile strength). |
| Appositional growth | Cartilage growth where new matrix is laid down on the surface by cells in the perichondrium. |
| Interstitial growth | Cartilage growth where chondrocytes within lacunae divide and secrete new matrix, expanding cartilage from within. |
| Seven functions of bone | Support, protection, anchorage (levers), mineral storage, blood cell formation (hematopoiesis), triglyceride (fat) storage, hormone production (osteocalcin). |
| Axial skeleton | Portion of the skeleton forming the long axis of the body: skull, vertebral column, rib cage. |
| Appendicular skeleton | Bones of the upper and lower limbs and the girdles that attach them to the axial skeleton. |
| Long bone | Bone longer than it is wide with a medullary cavity extending the length of the shaft; most limb bones. |
| Short bone | Cube-shaped bone; examples include wrist and ankle bones; includes sesamoid bones that form within tendons. |
| Flat bone | Thin, flat, slightly curved bone; examples include sternum, ribs, and most cranial bones. |
| Irregular bone | Bone with complicated shape; examples include vertebrae and hip bones. |
| Diaphysis | Tubular shaft of a long bone; compact bone surrounding a central medullary cavity (yellow marrow in adults). |
| Epiphysis | Bone ends of a long bone; compact bone externally and spongy bone internally; covered with articular cartilage at joint surfaces. |
| Periosteum | Double-layered membrane covering external bone surfaces (except joints); outer fibrous layer and inner osteogenic layer with stem cells. |
| Endosteum | Delicate connective tissue membrane lining internal bone surfaces; covers trabeculae and lines canals; contains osteogenic cells. |
| Red bone marrow | Hematopoietic tissue found in trabecular cavities of spongy bone and diploë of flat bones; most active in flat and irregular bones in adults. |
| Osteogenic cells | Mitotically active stem cells in periosteum and endosteum that can differentiate into osteoblasts or bone-lining cells. |
| Osteoblasts | Bone-forming cells that secrete unmineralized bone matrix (osteoid) composed of collagen and calcium-binding proteins. |
| Osteocytes | Mature bone cells in lacunae that maintain matrix and act as stress or strain sensors. |
| Bone-lining cells | Flat cells on bone surfaces that help maintain matrix; periosteal cells externally and endosteal cells internally. |
| Osteoclasts | Giant multinucleate cells derived from hematopoietic stem cells; responsible for bone resorption. |
| Osteon | Structural unit of compact bone; concentric lamellae around a central canal. |
| Canaliculi | Hairlike canals connecting lacunae to each other and to the central canal. |
| Spongy bone | Trabecular bone organized along lines of stress; nourished by capillaries in endosteum. |
| Osteoid | Organic portion of bone matrix secreted by osteoblasts; provides tensile strength and flexibility. |
| Hydroxyapatites | Calcium phosphate crystals that make up 65% of bone mass; provide hardness and compression resistance. |
| Endochondral ossification | Bone replaces hyaline cartilage; forms most bones below the skull. |
| Intramembranous ossification | Bone develops from fibrous membranes; forms flat bones like skull and clavicles. |
| Epiphyseal plate | Cartilage plate responsible for longitudinal bone growth; consists of five zones. |
| Wolff’s law | Bone grows or remodels in response to mechanical stress. |
| PTH (parathyroid hormone) | Hormone released when blood calcium is low; stimulates osteoclasts to release calcium. |
| Calcitonin | Hormone released when blood calcium is high; lowers calcium at high doses. |
| Osteoporosis | Condition where bone resorption exceeds deposition, leading to porous, fragile bones. |
| Stages of fracture repair | Hematoma → fibrocartilaginous callus → bony callus → remodeling. |