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Pharm
Exam 3
| Term | Definition |
|---|---|
| PPI (omeprazole, pantoprazole) | Blocks basal and stimulated acid production, and reduce gastric acid secretion by irreversibly inhibiting the enzyme that produces gastric acid. acts faster and reduces more gastric acid than H2 receptor. Should not be used long term, |
| Famotidine (H2 receptor) | promotes gasteric and/or duodenal ulcer healing by suppressing secretion of gastric acid. can provide quick symptom relief. doesn't inhibit P450 |
| Cimetidine (H2 receptor) | promotes gasteric and/or duodenal ulcer healing by suppressing secretion of gastric acid. can provide quick symptom relief. inhibits P450 |
| Aluminum hydroxide (antacid) | |
| Calcium carbonate (antacid) | |
| Amoxicillin (antibiotic) | |
| Clarithromycin (antibiotic) | |
| Sucralfate (mucosal protectant) | promotes ulcer healing by creating a protective barrier against acid and pepsin for up to 6 hours. does not neutralize acid and does not decrease acid secretion. no acid-neutralizing capacity and does not decrease acid secretion. |
| Misoprostol (mucosal protectant) | used to prevent gastric ulcers caused by long-term therapy with NSAIDs. decreases acid secretion, increases the secretion of bicarbonate and protective mucus, and promotes vasodilation to maintain submucosal blood flow |
| aluminum hydroxide (antacids) | neutralize o |